Postdoctoral researcher

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European Commission › EURAXESS › Jobs & Funding › Postdoctoral researcher
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22/06/2022
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Postdoctoral researcher
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Postdoctoral researcher
Application Deadline: 03/08/2022 00:00 - Europe/Brussels
Contact Details

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Company
Erasmus MC (University Medical Center Rotterdam)

• 
  WEBSITE
  https://www.academictransfer.com/314343/postdoctoral-researcher/apply/#apply
  

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• 
  ORGANISATION/COMPANY
  Erasmus MC (University Medical Center Rotterdam)
  
• 
  ORGANISATION TYPE
  Higher Education Institute
  
• 
  WEBSITE
  http://www.erasmusmc.nl/
  

• 
  COUNTRY
  Netherlands
  
• 
  CITY
  Rotterdam
  
• 
  POSTAL CODE
  3015 CE
  
• 
  STREET
  's-Gravendijkwal 230
  

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• 
  ORGANISATION/COMPANY
  Erasmus MC (University Medical Center Rotterdam)
  
• 
  RESEARCH FIELD
  Medical sciences
  
• 
  RESEARCHER PROFILE
  Recognised Researcher (R2)
  
• 
  APPLICATION DEADLINE
  03/08/2022 00:00 - Europe/Brussels
  

• 
  LOCATION
  Netherlands › Rotterdam
  
• 
  TYPE OF CONTRACT
  Temporary
  
• 
  HOURS PER WEEK
  36.0
  

OFFER DESCRIPTION

Germline mutations in the transcription factor GATA2 result in bone marrow failure with a high predispostion for leukemia. We have modeled this disease in zebrafish by mutating Gata2b, affecting both embryonic and adult hematopoiesis. To be able to establish future gene therapy treatment options for these patients, we need to understand if adult restoration of the Gata2 deficiency is sufficient to abrogate disease ontogeny. For this we have generated a mutant that, upon CRE activation, reexpresses Gata2b from its endogenous locus. The goal of this project is to investigate if reexpression of Gata2b restores the adult leukemia phenotype. The project involves embryonic and adult zebrafish manipulation, flowcytometry analysis and state-of-the-art molecular analyses. ]

More Information
Additional Information
Benefits

• The gross monthly salary amounts a maximum of € 4.800,- (scale 10), depending on your level of education and relevant experience, based on a full-time working week of 36 hours.
• Excellent fringe benefits, such as a 13th month that is already paid out in November and a induvidual travel expense package.
• Pension insurance with ABP. We take care of approximately 2/3 of the monthly contribution.
• Special benefits, such as a incompany physiotherapist and bicycle repairer. And there is also a sports club where you can work on your fitness after work.

Selection process

For more information about this position, please contact Emma de Pater, PI, phone number: +31-107037560 For queries regarding your application, please contact Donja Grootscholten, recruiter, by phone number: +31 (0)6 500 310 06 .
If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

Additional comments

For more information about this position, please contact Emma de Pater, PI, phone number: +31-107037560 For queries regarding your application, please contact Donja Grootscholten, recruiter, by phone number: +31 (0)6 500 310 06 .
If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website.

Web site for additional job details

https://www.academictransfer.com/314343/

Requirements
Offer Requirements
Specific Requirements

The perfect candidate holds a PhD in the life sciences and has experience in zebrafish embryonic development and micromanipulation and experience using flowcytometry. Applicants with a background in (malignant) hematopoiesis and embryonic development are also encouraged to apply.

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Work location(s)
1 position(s) available at
Erasmus MC
Netherlands
Rotterdam
3015 CE
's-Gravendijkwal 230
Open, Transparent, Merit based Recruitment procedures of Researchers (OTM-R)

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EURAXESS offer ID: 803087
Posting organisation offer ID: 314343

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