Postdoc Position in single cell analysis of cell differentiation in vivo (1.0 FTE)

The van den Heuvel lab currently offers a post-doctoral research position in Developmental Biology. The focus of the project will be to reveal the regulatory logic of cellular decision making in the context of animal development. Specifically, we seek to better understand how precursor cells commit to a differentiated state, and how this is coordinated with a permanent arrest of cell division. To address these questions, we will perform detailed quantitative analyses of native cells during their differentiation trajectory in the round worm Caenorhabditis elegans (C. elegans), in combination with sophisticated genetic manipulation. This project is part of a consortium effort and incorporates the latest technologies in transcriptome, epigenome, and proteome analysis, in close collaboration with specialists in single-cell analysis (Korswagen and van Oudenaarden labs, Hubrecht Institute), proteomics techniques (Vermeulen lab, Radboud University Nijmegen) and computational modeling (ten Tusscher lab, Utrecht University).

You, as post-doctoral researcher, will become part of the highly interactive Developmental Biology community at Utrecht University. This will include daily interactions with fellow researchers in the van den Heuvel, Boxem and Ruijtenberg labs, with graduate students and post-docs who work on related topics with one of the consortium partners, and with other researchers within the Institute of Biodynamics and Biocomplexity (e.g.: Akhmanova, Kapitein, Baubec, ten Tusscher labs) or broader Utrecht University campus.