Imaging distributions of radiolabeled molecules using PET and SPECT scaners is key for discovering mechanisms of disease, new pharmaceuticals and diagnostic tracers. The application of radiotracers that combine a predictive biomarker with a therapeutic agent -theranostic tracers– and the demand for multi-tracer imaging are witnessing an impressive growth. The postdoc will be part of a project that aims at developing a novel small animal PET-SPECT scanner that
- enables improved quantitative tomography for virtually any available gamma, positron or co-emitting tracer molecule (30 keV - 1 MeV energy range),
- allows quantitative imaging of many new tracer combinations including multiple PET isotopes, and
- has an order of magnitude higher effective sensitivity for high-energy gamma emitters than current scanners.
To enable such universal molecular nuclear tomography platform the postdoc will explore (1) innovative collimator designs (2) image reconstruction with universal energy-dependent models for high-energy and co-emitting gamma and positron emitters (3) utilization of new detectors.
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