Postdoc in Quantitative Cell Biology/Biochemistry/Bioengineering (1.0 FTE)

We are looking for a highly motivated and enthusiastic Postdoctoral fellow with a strong background in biochemistry, biophysics, bioengineering or closely related fields to join the Cell Cycle Dynamics group of Dr Julia Kamenz.

In a human body, billions of cells divide every single day. Errors during cell division or uncontrolled cell proliferation can have detrimental consequences including cancer development. Our research focuses on understanding the molecular mechanisms underlying the regulation of cell proliferation and cell division. These studies include (1) the intricate regulation of the kinases and phosphatases involved in the processes of cell division, (2) the impact of post-translational modifications in regulating cell division – in particular phosphorylations – and (3) studying the complex signaling networks surveying and controlling cell cycle progression. Specifically, this project will be focusing on developing new techniques to interrogate the signaling dynamics of cell cycle progression and cell cycle checkpoints using the frog egg extract system.

In the laboratory, we combine a variety of cell biological, biochemical and systems biological approaches including Xenopus laevis egg extracts, enzyme biochemistry, fluorescence live cell imaging of human cells and computational modelling. Among others, the Postdoctoral fellow will have access to state-of-the-art microscopes, microfluidics, mass spectrometry, tissue culture and animal facilities.

The Cell Cycle Dynamics group is embedded in the Molecular Systems Biology unit at the Groningen Biomolecular Sciences and Biotechnology Institute, which provides an inspiring, interdisciplinary and collaborative research environment.