Postdoc Center for Proteomics and Metabolomics

27 May 2023
Job Information

Organisation/Company

Leiden University Medical Center (LUMC)

Research Field

Medical sciences

Researcher Profile

Recognised Researcher (R2)

Country

Netherlands

Application Deadline

18 Jun 2023 - 21:59 (UTC)

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

36.0

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

As a postdoc you will investigate intestinal glycans in inflammatory diseases by mass spectrometry imaging. In the multidisciplinary GlycanTrigger project, we aim to gain new molecular insights in the transition from healthy to chronic inflammation in patients with IBD. A specific focus lies on the changes in glycosylation of specific cell types involved in this transition. To accurately study the role of protein and lipid glycosylation at the single-cell level, new methods need to be developed that allow spatial and in-depth characterization of glycosylated molecules. You will develop on-tissue mass spectrometry imaging (MSI) methods for in-situ N-, O- and lipid-glycan analysis. The in-situ methods need to be complemented with off-tissue analyses with sufficient analytical sensitivity and depth-of-coverage, e.g. LC-MS-based methods. Ultimately, developed methods will be applied to a well-defined cohort of IBD patients to get insight into the role of glycosylation in IBD. This will be done in collaboration with both local clinicians and international partners from the GlycanTrigger consortium.

Requirements
Specific Requirements

·         You have obtained your PhD in mass spectrometry imaging or analytical glycoscience (or will do so on very short term);

·         You have a keen interest in, and ample experience with, mass spectrometry imaging;

·         Affinity and experience with computer scripting, and data analysis are a big plus;

·         You must be fluent in English, pro-active and performance driven, structured and accurate, and have good communication and writing skills

Additional Information
Benefits

You will be employed on the basis of 36 hours per week. Your salary is based on your education and experience and is a maximum of  € 5,088  gross per month for a full time position (scale 10 in the Collective Labour Agreement for University Hospitals).

Additional comments

Contact

Dr. Noortje de Haan – assistant professor, Center for Proteomics and Metabolomics

n.de_haan@lumc.nl

 

Applications from employment/recruitment agencies will not be considered.

Website for additional job details

https://www.academictransfer.com/328419/

Work Location(s)

Number of offers available

1

Company/Institute

LUMC

Country

Netherlands

City

Leiden

Postal Code

2333 ZA

Street

Albinusdreef 2

Where to apply

Website

https://www.academictransfer.com/328419/postdoc-center-for-proteomics-and-metab…

Contact

City

Leiden

Website

http://www.lumc.nl/

Street

Albinusdreef 2

Postal Code

2333 ZA

STATUS: EXPIRED