Post-doc position in Computational Systems Biology

The Department of Developmental BioEngineering at the University of Twente (Enschede, the Netherlands) is looking for a computational modeler to describe and predict factors for better stem cell differentiation for heart tissue engineering applications. This project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the University of Twente.

Current animal and cell culture models are not accurate enough to predict the efficacy and toxicity of drugs. In this research project, titled ‘Advanced bioengineering strategy for production of human miniature hearts’ , a multidisciplinary team consisting of (developmental) biologists, bioinformaticians, and mathematicians will encapsulate human stem cells in hollow miniature spheres made from hydrogel and use single cell OMICs analysis to make digital twins of the miniature hearts. The digital twins generated in this project allow investigating heart development and predicting the response of the heart to medication.

Are you interested to be part of our team? Please send your application and include:

• A motivation letter explaining your interest and qualifications for this position;
• A detailed CV (resume) with a publication list;
• The name and e-mail address/telephone number of two references;
• A copy of your PhD-thesis and two of your related scientific papers;
• We may request a TOEFL or IELTS score to verify sufficient skills in English.

For inquiries about this position and our offer you can contact Janine Post, PhD ([email protected]). An application for this position should be accompanied by motivation and curriculum vitae, including a list of publications (when applicable) and can be submitted via the button below.

Department of Developmental BioEngineering
The department of Developmental BioEngineering is a research group with a highly international character. The main goal of this group is to investigate novel and challenging technologies in the field of Regenerative Medicine, which can be used for tissue repair. Research focuses on i) Fundamental aspects of joint and cartilage homeostasis, ii) Cell therapy for treatment of joint disorders, and iii) Injectable, in situ gelating extracellular matrices for soft tissue repair, iv) computational models for tissue development and homeostasis. DBE
The project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the same university (UT). This department focuses on topics in the area of dynamical systems, numerical analysis and scientific computing, and systems and control, and in particular, their relation with data science. EEMCS

The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.