Postdoctoral Fellow in Computational Biology/Statistical Bioinformatics

Organisation/Company

University of Luxembourg

Department

Human Resources

Research Field

Biological sciences » Biology
Computer science » Other
Engineering » Biomaterial engineering
Physics » Biophysics

Researcher Profile

Recognised Researcher (R2)

Country

Luxembourg

Application Deadline

2 Jun 2023 - 00:01 (Europe/Luxembourg)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

40

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

Yes

The Luxembourg Centre for Systems Biomedicine (LCSB) was created within the Health Technologies Initiative from the Government of Luxembourg as one of the research priorities of the University of Luxembourg. The LCSB is an Interdisciplinary Centre of the University independent of the faculties. It combines experimental and computational approaches to analyze complex biological systems and disease processes from a systems biology perspective.

The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary and together we contribute to science and society.

The Computational Biology Group (CBG) provides the LCSB with a solid infrastructure in developing theoretical methods for computational modeling of biomedical problems (e.g., in the area of regenerative medicine and stem-cell biology). The CBG includes researchers with theoretical, computational and wet lab backgrounds, thereby providing a unique interdisciplinary environment.

The CBG seeks a highly skilled and motivated postdoctoral fellow to work on an exciting project that aims at developing a computational framework for modeling molecular interactions to elucidate pathological mechanisms of Mitochondrial DNA-associated Leigh Syndrome (MILS), a rare severe pediatric disease affecting the central nervous system with typical manifestation in the form of intellectual and movement disturbances.

In particular, the successful candidate will develop computational and statistical models using multi-omics data (including single-cell transcriptomics, proteomics, and metabolomics data) to identify potential molecular targets for subsequent drug repurposing in the context of MILS. The modeling methodologies include, but not limited to, network biology, bioinformatics, information theory, statistical modeling and machine learning, agent-based modeling and others.

The project is funded by European Joint Programme for Rare Diseases and includes a consortium of international collaborators, including medical practitioners with existing record of achievements in treatment of MILS. The consortium aims at discovery of new drugs for MILS using high-throughput scanning of existing compounds/drugs on stem-cell derived neural cells and brain organoids.

In addition, the successful candidate will curate the group’s contribution to the consortium and provide it with statistical and computational support which requires ability to work with various professional backgrounds (biologists, doctors and others). Finally, he/she will participate in the project management and planning, including supervision of Ph.D. students and reporting of scientific results.

Essential skills and qualities:

• Ph.D. degree in biology, computer science, engineering, physics or related discipline
• Strong computational skills (demonstrable project in the relevant field)
• A strong first-author publication record in the relevant field
• Excellent communication skills and working knowledge of English

Ideal skills:

• A record of first-author publications in the fields of bioinformatics and/or computational biology
• Prior experience in mathematical modeling of biological networks
• Experience in working in multi-disciplinary research settings

• Opportunity to do highly interdisciplinary research and solve complex biomedical problems within a highly dynamic research institution (LCSB) and in collaboration with internationally recognized partners
• International and multi-lingual environment
• Very competitive salary and a range of social benefits
• 1-year contract with extension to 3 years upon satisfactory performance

Find out more about us!

• Contract type: Fixed Term Contract 12 Month (extendable)
• Work hours: Full Time 40.0 Hours per Week
• Location: Belval
• Job reference: UOL05712

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 81072 (full time)

Applications should contain the following documents:

• A detailed curriculum vitae
• A cover letter

We ensure a full consideration for applications received by 1st of June 2023. Please apply formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR)
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

• Find out more about the University
• Addresses, maps & routes to the various sites of the University

University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and has more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.

For further information, please contact: Prof. Dr. Antonio del Sol, E-mail: antonio.delsol@uni.lu

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Research Field

Computer science » Other

Education Level

PhD or equivalent

Research Field

Engineering » Biomaterial engineering

Education Level

PhD or equivalent

Research Field

Physics » Biophysics

Education Level

PhD or equivalent

Number of offers available

1

Company/Institute

University of Luxembourg

Country

Luxembourg

Website

https://uniluxembourg.recruitmentplatform.com/apply.html?jobId=P4CFK026203F3VBQ…

State/Province

Grand Duché de Luxembourg

City

Luxembourg

Website

http://www.uni.lu

Street

2, avenue de l'Université

Postal Code

4365

E-Mail

beatrice.delporte@uni.lu