Laboratory Technician on project in Translational Neuroscience

Updated: 4 months ago
Job Type: FullTime
Deadline: 15 Feb 2022

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and counts more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.

The Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg is a highly dynamic, multilingual and international working environment at campus Belval. The Translational Neuroscience Group, led by Prof Rejko Krüger, creates a translational bridge between fundamental and the clinic with a focus on Parkinson’s disease research, with the aim to improve diagnosis and therapy to help patients in Luxembourg and beyond. We are currently looking for an energetic, highly motivated Laboratory Technician for working on collaborative fundamental biology research projects in Parkinson’s disease (PD). 

Your Role...

The Laboratory technician will support the research team in Translational Neuroscience regarding the organization of the lab (ordering, supply), perform experiments, obtain training in maintenance of lab automation (automated pipetting, cell culture) and analyze results to assist in research and development of cellular models of Parkinson’s disease (human cell lines, fibroblasts, and induced pluripotent stem cells) at LCSB.

In particular, the technician in this role will support a project of early drug development in in vivo and in vitro models. These models will be used to test the efficacy of pharmacological intervention to revert cellular phenotypes. The project includes development of a screening assay, in vitro high throughput compound screenings using high content imaging readouts, in vivo drug testing with subsequent tissue dissection and analysis by molecular biology methods (qPCR and Western blot).

Specific tasks can include:

  • Place orders for lab supply and inventory for laboratory use
  • Make-up and maintain stock/working chemical solutions and growth media
  • Work in vivo (mice) & in vitro (bacteria and cell culture)
  • Conduct cultures of human induced pluripotent stem cells (iPS cells)
  • Extract DNA, RNA, proteins from iPS cells. These will be used for subsequent analyses including transcriptomics, proteomics, and metabolomics
  • Perform molecular biology experiments such as plasmid construction, cloning, PCR, qPCR
  • Perform various biochemical assays and protein purifications
  • Conduct immunofluorescence stainings of various cell types
  • Perform differentiation of iPS cells into various lineages, including dopaminergic neurons
  • Maintain a clean laboratory setting
  • Perform flow cytometry
  • BCA protein quantification assay & Western blot

What we expect from you…
  • A technical degree or equivalent in molecular biology, microbiology, biochemistry, bioengineering, biology or similar
  • A certification for laboratory animal work
  • Excellent organizational skills
  • Good computer skills for standard software (Excel, Word, etc) and specific tools (LaTeX, ImageJ Fiji, Graphpad Prism)
  • Flexible regarding research stays in collaborators’ research laboratories
  • Good command of English and French or German; knowledge Luxembourgish is considered to be an advantage

We offer...

  • An enthusiastic interdisciplinary team of basic scientists and clinical researchers in the area of Parkinson’s disease/Neurodegeneration
  • Opportunity to participate in the development of new concepts for the understanding and modulation of Parkinson’s disease as a common disorder
  • An excellent international network in the area of neurodegenerative research

In Short...
  • Contract Type: Fixed Term Contract 24 Month
  • Work Hours: Full Time 40.0 Hours per Week
  • Ideal starting date: April 2022
  • Location: Belval
  • Internal Title: Research support technician
  • Job Reference: UOL04718

How to apply...

Applications (in English) should contain the following documents:

  • Detailed Curriculum Vitae
  • Cover letter mentioning the reference number
  • Description of past research experience and future interests

We ensure a full consideration for applications received by 15/02/2022.

Please apply formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

In return you will get…
  • Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR). 
  • A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure.
  • A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

Further information...

Please contact Dr. Ibrahim BOUSSAAD for further information:

View or Apply

Similar Positions