The Fellowship implies carrying out the activities briefly mentioned below at Dipartimento di Scienze Cliniche e di Comunità dell’Università degli Studi di Milano and under the supervision of Prof. Sergio Abrignani within the research programme “Bioinformatic dissection of tumor-infiltrating lymphocytes functional phenotype”, within the research project n. CP2_12/2018 financed by Fondazione Regionale per la Ricerca Biomedica entitled “A regional oncology network addressing the emerging problem of colorectal cancer in young individuals using an integrative omics approach to decipher mechanisms of cancer immunoediting as candidate targets of new therapies”, of the activities mentioned below:
1) Characterization of tumor microenvironment at the single-cell resolution.
2) Tumour-infiltrating T lymphocytes transcriptional and T cell receptor (TCR) repertoire profiling.
3) Implementation of bioinformatics tools for the analysis of single-cell sequencing data.
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