Postdoctoral fellow – T cell genome integrity in human cancer Lugli Lab, Humanitas Research Hospital, Milan, Italy
1 Feb 2024
Job Information
- Organisation/Company
Humanitas Research Hospital- Department
Immunology- Research Field
Biological sciences » Biological engineering
Medical sciences » Cancer research
Biological sciences » Biology- Researcher Profile
Recognised Researcher (R2)- Country
Italy- Application Deadline
30 Apr 2024 - 12:00 (Europe/Rome)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
40- Offer Starting Date
1 May 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
We are seeking a highly-motivated, outstanding junior or senior postdoc to join our lab at the Humanitas Research Hospital to study the role of genome integrity in memory T cell differentiation and immunosuppression in the context of human cancer and in response to immunotherapy. Humanitas hosts a scientific community of more than 300 scientists with interests ranging from immunology to genomics, cardiovascular biology and neurobiology and is one of the most visible and expanding research centers in Italy.
We have identified novel molecular signals regulating the genome integrity of stem-like T cells and regulatory CD4+ T cells (Tregs) in the tumor microenvironment that we want to manipulate, so to obtain long-lived T cell responses that are resistant to immunosuppression. Several human samples from cancer patients are routinely available for this purpose thanks to collaborations with the Humanitas Hospital. The Lab is specialized in the identification and characterization of novel lymphocyte subsets by using high-dimensional single cell analysis, and advanced bioinformatics. Access to Humanitas facilities (flow cytometry, genomics, microscopy, histology, tissue mass cytometry, metabolomics, BSL-3, SPF mouse house, grant office) will be granted. The position is available for up to 5 years.
The optimal candidate would have (or be in the process to obtain) a PhD in molecular biology, DNA technology, immunology, biotechnology or related disciplines, and at least one first-authored paper submitted to a top-tier journal. Preference will be given to candidates with a strong background in molecular biology. Candidates not residing in Italy are eligible to 50% tax discount per Italian law.
To apply, please send a motivation letter explaining why you want to join our lab, a 2-page CV (no Europass format), and the contact information (or letters of recommendation) of at least two referees to Dr. Enrico Lugli ([email protected] ).
Selected references
Requirements
- Research Field
- Biological sciences » Biological engineering
- Education Level
- PhD or equivalent
Skills/Qualifications
The optimal candidate would have (or be in the process to obtain) a PhD in molecular biology, DNA technology, immunology, biotechnology or related disciplines, and at least one first-authored paper submitted to a top-tier journal. Preference will be given to candidates with a strong background in molecular biology.
Specific Requirements
To apply, please send a motivation letter explaining why you want to join our lab, a 2-page CV (no Europass format), and the contact information (or letters of recommendation) of at least two referees to Dr. Enrico Lugli ([email protected] ).
- Languages
- ENGLISH
- Level
- Good
Additional Information
Benefits
Candidates not residing in Italy are eligible to 50% tax discount per Italian law.
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Humanitas Research Hospital
- Country
- Italy
- City
- Pieve Emanuele
- Postal Code
- 20080
- Street
- via montalcini 4
- Geofield
Where to apply
[email protected]
Contact
- City
Rozzano, Milan- Website
https://www.humanitas-research.com/groups/enrico-lugli-group/- Street
via Manzoni 113
[email protected]
STATUS: EXPIRED
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