NEONATE: uNveiling thE genetic causes Of recurreNt implAnTation failurE

Updated: 27 days ago
Deadline: 16 Jun 2024

18 May 2024
Job Information
Organisation/Company

Ministero dell’Università e della Ricerca MUR
Research Field

Biological sciences
Researcher Profile

Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)
Country

Italy
Application Deadline

16 Jun 2024 - 23:59 (UTC)
Type of Contract

To be defined
Job Status

Not Applicable
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The breakthrough of assisted reproductive technology (ART) in recent scientific history has allowed
couples previously unable to conceive to achieve viable pregnancy. Although ART has improved outcomes
for struggling couples, a new challenge has emerged: recurrent implantation failure (RIF). RIF is defined as
the failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a woman
under the age of 40. RIF is unexplained in nearly 30% of cases and the mechanisms of this unexplained
infertility are not well-established. Balanced structural rearrangements, such as inversions and
translocations, are one of the principal genetic factors in reproductive failure. These aberrations may
show no obvious clinical manifestations and remain undetected across multiple generations, although
carriers may experience recurrent adverse pregnancy outcomes as a consequence of forming unbalanced gametes.


Requirements
Additional Information
Eligibility criteria

Eligible destination country/ies for fellows:

  • Italy
  • OTHER

Eligibility of fellows: country/ies of residence:

  • Italy
  • OTHER

Eligibility of fellows: nationality/ies:

  • Italy
  • OTHER

Website for additional job details

https://reclutamento.ict.uniba.it/assegni-di-ricerca

Work Location(s)
Number of offers available
1
Company/Institute
Ministero dell’Università e della Ricerca MUR
Country
Italy
Geofield


Where to apply
Website

http://www.prin.mur.gov.it

Contact
City

Roma
Website

http://www.prin.mur.gov.it

STATUS: EXPIRED

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