Improving sensory characteristics through cocrystallization of antibiotic molecules for paediatric use

Updated: about 1 month ago
Deadline: 26 Apr 2024

27 Mar 2024
Job Information
Organisation/Company

Università degli Studi di Trieste
Department

HR - Academic Staff
Research Field

Chemistry » Other
Researcher Profile

First Stage Researcher (R1)
Country

Italy
Application Deadline

26 Apr 2024 - 23:59 (Europe/Rome)
Type of Contract

Temporary
Job Status

Not Applicable
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Reference Number

24ar364-6PRINPNRR
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The synthesis of cocrystals is a rapidly growing branch of supramolecular chemistry, which brings the engineering of new crystalline forms to a higher level of versatility compared to single-component crystals. The use of cocrystallization technology for improving sensory characteristics of drugs, including palatability, has been so far neglected. In this project, the most important supramolecular synthetic strategies will be explored during to obtain functional solids with improved properties of specific antibiotics. The project therefore will consist on the selection of a molecular library containing molecules that present suitable functional groups for cocrystallization and, at the same time, the required macroscopic properties such as sweeteners and permeability enhancers. The new cocrystalline forms obtained will be synthetized and characterized using different solid-state techniques including calorimetric (DSC), diffraction (PXRD, SCXRD) and microscopy techniques (SEM, TEM).


Requirements
Research Field
Chemistry » Other
Education Level
Master Degree or equivalent

Additional Information
Website for additional job details

https://web.units.it/concorsi/ricerca/conc-51331

Work Location(s)
Number of offers available
1
Company/Institute
University of Trieste
Country
Italy
City
Trieste
Geofield


Where to apply
Website

https://pica.cineca.it/units

Contact
City

Trieste
Website

https://www.units.it/ateneo/bandi
E-Mail

[email protected]

STATUS: EXPIRED

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