Exosomes as a source of molecular monitoring in chronic myeloid leukemia patients in molecular response deep sustained symptoms that interrupt treatment
20 Apr 2024
Job Information
- Organisation/Company
Dipartimento di Medicina traslazionale e di precisione- Research Field
Medical sciences » Medicine- Researcher Profile
Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)- Country
Italy- Application Deadline
18 May 2024 - 23:59 (UTC)- Type of Contract
To be defined- Job Status
Not Applicable- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Tyrosine kinase inhibitors (TKIs) have had a dramatic impact on patient management and monitoring
with chronic myelogenous leukemia (CML). The term “treatment-free remission” (TFR) was introduced in the TKI era for
indicate discontinuation of treatment after achieving a stable, deep and long-lasting molecular response
duration. Exosomes have attracted interest due to the discovery of their role in intracellular communications. In
in particular, exosomes are small lipid nanoparticles derived from endosomes, secreted by exocytosis from the majority
part of the cells. The composition of exosomes reflects that of the mother cells and their release occurs both
spontaneously or after induction. Exosomes carry genomic DNA, miRNA, mRNA and proteins into the blood peripheral or in other fluids (i.e. saliva).
Requirements
Additional Information
Eligibility criteria
Eligible destination country/ies for fellows:
- Italy
Eligibility of fellows: country/ies of residence:
- EUROPE
Eligibility of fellows: nationality/ies:
- Italy
- Website for additional job details
https://web.uniroma1.it/trasparenza/bandi_trasparenza
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Dipartimento di Medicina traslazionale e di precisione
- Country
- Italy
- Geofield
Where to apply
https://xup-dmtp.cloud
Contact
- City
ROME- Website
https://web.uniroma1.it/dmtp
STATUS: EXPIRED
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