Co-tutored ESR position between the University of Insubria – Como, and the University of Regensburg...

A co-tutored ESR position is open between the University of Insubria – Como, and the University of Regensburg, starting October 1st 2022 – December 1st 2022 for 36 months.

The deadline for submitting the application is August 31st 2022. The candidates must contact and apply as soon as possible by sending a CV, transcript records, and a motivation letter to the two supervisors of the doctoral project:

Prof. Dr. Oliver Reiser (University of Regensburg) : [email protected]

Prof. Dr. Umberto Piarulli (Insubria University) : [email protected]

Objectives of the doctoral project

At Insubria University, the ESR will be involved in the design and synthesis of antitumor conjugates consisting of small molecules or peptides modulating the tumor protein p53 activity and av b3 or a5 b1 integrin ligands, or prostate specific membrane antigen (PSMA) ligands. Linking and release strategies will be optimized and biological studies in cancer cell lines will be performed. This project is part of the MSCA-ETN MagicBullet Reloaded.

Further information can be found at https://www.uni-bielefeld.de/fakultaeten/chemie/projects/magicbulletreloaded or by contacting Prof. U. Piarulli.

At the University of Regensburg, the ESR will be involved in the (photo)catalytic synthesis of small ring amino acids and their evaluation as building blocks for peptides.

Candidate profile:

• University degree which allows to pursue doctoral studies in Chemistry (e.g. MSc in Chemistry, Organic Chemistry or Medicinal Chemistry).
• a strong knowledge and practical experience in synthetic organic chemistry, documented by MSc thesis or scientific publications.
• practical experience in analytical methods (NMR, MS, HPLC).
• excellent knowledge of the English language (comprehension, speaking and writing).
• good abilities in scientific writing (reports, manuscripts).
• team-oriented and cooperative working attitude.
• motivation and willingness to work in an international environment and in two research groups.
• motivation and willingness to present scientific results in conferences and to publish in scientific journals.
• Preferable additional qualifications
• Background in medicinal chemistry and peptide chemistry.
• Basic knowledge in biological assays.
• Experience with working in a team.

Eligibility criteria

All applicants must be Early-Stage Researchers (ESRs) who are in the first four years (full-time equivalent research experience) of their research careers, starting from the date when the M.Sc. degree (or similar) was awarded. They must not hold a doctoral degree.

Persons from any nationality may apply, but transnational mobility is indispensable: You may only apply if you did not reside or carry out your main activity (such as work or study) in Italy for more than 12 months within the last 3 years. Short stays such as holidays or compulsory national service are not taken into consideration.

Employment Conditions

A co-tutoring agreement will be established between the two Academic Institutions for the Candidate PhD thesis

The first 16 months at Insubria University will be funded by the MSCA-ETN MagicBullet Reloaded (https://www.uni-bielefeld.de/fakultaeten/chemie/projects/magicbulletreloaded ). The selected candidate will receive a 16-month, full-time employment contract as per Marie Sklodowska-Curie Actions (MSCA) regulations for early stage researchers, starting October 1st 2022 – December 1st 2022. (Further information regarding eligibility and salary can be found on the MSCA website ).

Enquire for further information contacting:

[email protected]

[email protected]

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