Molecular and morphological studies aimed at characterizing the Adverse Outcome Pathways (AOPs) related to the exposure to nanoparticles and nano-enabled products of metal and polymeric structure. In vitro 3D systems of the primary barriers (pulmonary, skin, intestinal) will be prepared using human cell co-cultures. They will be exposed to the nanomaterials under physiological conditions representative of the in vivo conditions (artificial sweat, exposure at the air-liquid interface in presence of the pulmonary surfactant, etc…). Afterwards, biochemical and molecular analyses will be performed to evaluated the toxicological pathways related to oxidative stress and inflammatory events. The cell cultures will be finally analysed by light and electron microscopy, also applying correlative microscopy techniques to characterize the nano-bio-interaction modalities
Bioinformatician For Analysis Of Single Cell Rna Sequencing Datasets, University of Groningen, Netherlands, about 7 hours ago
Department Pathology & Medical Biology Work location Groningen Apply no later than 14 March 2021 Working environment The project will be embedded within the Groningen Research Institute of Asthma ...
Analyst Stem Cell Platform, Leiden University, Netherlands, about 12 hours ago
One day left to apply The Faculty of Science, Leiden Academic Centre for Drug Research (LACDR) is looking for an Analyst - Stem cell platform Project description The Leiden Academic Center for Dru...
Lung On Chip To Capture Cell Interplay In Chronic Obstructive Lung Disease, Katholieke Universiteit Leuven, Belgium, 23 days ago
The PhD project belongs to a research project dealing with the use of lung-on-a-chip as a dynamic tool to capture interplay between airway and vascular cells in their microenvironment. The project...
Researcher, Bio Informatics Molecular Biologist, Karolinska Institute, Sweden, about 16 hours ago
Do you want to contribute to improving human health? Our working environment The research group of Associate Prof.Hareth Nahi is a world-leading cross disciplinary team investigating multiple mye...
Technician – Light Microscopy And Image Analysis Specialist, Leiden University, Netherlands, about 12 hours ago
27 more days to apply The Faculty of Science, Leiden Academic Centre for Drug Research (LACDR) is looking for a Technician – Light Microscopy and Image Analysis Specialist Project description The ...
Assistant Professor/Associate Professor/Professor, Mechanobiology Institute, Times Higher Education, United Kingdom, 24 days ago
Job Description The Mechanobiology Institute (MBI) at the National University of Singapore (NUS) is a leading multidisciplinary institute devoted to developing new paradigms for understanding bio...