Post-doctoral researcher on SFI Precision Oncology Ireland Programme

Title: Post-doctoral researcher on SFI Precision Oncology Ireland Programme

Department: School of Pharmacy and Biomolecular Sciences (PBS)

Tenure: 3 years

Location: 123 St Stephen’s Green, PBS labs

Reporting to: Prof Tracy Robson

Salary: Level 2a- Point1-3 €38,631-41,025

Proposed Start Date: ASAP

Precision Oncology Ireland (POI) is a consortium of 5 Irish Universities, 6 Irish Charities, and 7 industry partners aiming to develop new diagnostics and therapeutics for personalised cancer treatment. Officially launched in November 2019, the consortium is part-funded by Science Foundation Ireland under their Strategic Partnership Programme. The combined SFI, charity, and industrial funding commitment will total €11.9 million over five years. This is the first time that researchers, charities and industry have combined forces in this way, with a joint view of achieving greater impact for patients by uniting investments in the POI programme.

This POI-funded research project is based in the School of Pharmacy and Biomolecular Sciences at RCSI and has matched funding from pHion Therapeutics . pHion Therapeutics was founded in 2017 and is focussed on a novel nano-technologies for enhanced drug delivery. The successful post-doctoral candidate will be involved in a pioneering cancer research project aimed at realising the therapeutic potential of a novel protein in ovarian cancer, where there is an unmet clinical need and where new therapies are urgently needed. Furthermore, the candidate will be working with clinical samples for rapid clinical translation of this technology.

Specifically, the primary duties of the post are:

• Carry out research in the cell and molecular biology area to establish the role of FKBPL in ovarian cancer. Key techniques will involve, tissue culture, cell and molecular biology techniques will include, RNA and protein analysis. Cell imaging including confocal microscopy and flow cytometry as well as significant animal work; the applicants will ideally have a personal animal license.
• Present regular progress reports to members of the research group, phion, POI or to external audiences to disseminate and publicise research findings.
• Prepare, in consultation with supervisor, material for publication in national and international journals and presentations at international conferences.
• Assist the PI in the preparation of funding proposals and applications to external bodies.
• Carry out routine administrative tasks associated with the research project/s to ensure those project/s are completed on time and within budget. These might include organisation of project meetings and documentation, financial control, risk assessment of research activities.
• Carry out undergraduate supervision, demonstrating or lecturing duties within the post holder's area of expertise and under the direct guidance of a member of academic staff.
• Read academic papers, journals and textbooks to keep abreast of developments in own specialism and related disciplines.