Scientist (PostDoc, m/w/d)

23.07.2021, Wissenschaftliches Personal

Chemical optimization of anti-infective drug molecules Vision | Trail blazing | Self-directedness | Excellence Is that you? Perfect! We offer the challenge you are seeking! Our profile: Our team mission is to meet the increasing threat of antibiotic resistance by developing innovative treatment options. Within a BMBF funded project, we seek to optimize a novel carbapenemase inhibitor class restoring the activity of the most widely used class of antibiotics (β-Lactams) in collaboration with the Helmholtz Institutes in Neuherberg (structure analysis via NMR and X-ray) and Braunschweig (synthetic chemistry). In addition, our inhibitor class combines beta-lactamase inhibition with standalone antibiotic activity in a unique manner. The focus of this project is the optimization of fragment-based inhibitors with respect to both activities.

Your profile:
- PhD degree in Chemistry, Biochemistry, Molecular Biotechnology, or Pharmacy with outstanding result
- Structure analysis and modelling expertise
- Experience in antibacterial compound optimization
- MedChem experience in industry setting is a plus
- Enthusiasm for translational science and entrepreneur personality
- Excellent team spirit, presentation and communication skills

Your tasks:
- Activity testing of inhibitory compounds
- Contribution to fragment based compound design and optimization
- Support in NMR and X.-ray structure analysis and modelling
- Antibacterial activity determination on WHO priority I pathogens
- MoA analysis of antibacterial activity
- Supervision of technical staff

We offer:
- Ambitious and innovation oriented team committed to antibacterial drug development
- Close collaboration with in house medical microbiology department and industry consultants
- Well-equipped laboratory in our institute close to Munich city center
- Full time position as scientist / PostDoc (m/w/d) from October 1st 2021.
- The position is currently secured for 18 months (salary according to TV-L), with the perspective of extension.
- Perspective to be part of a spin-out team

Application:
Are you excited to secure for infectious disease treatment?
Great! We are looking forward to your email application until August 10th 2021.

Dr. Hannelore Meyer, +89 15203112080, [email protected], http://www.mikrobio.med.tu-muenchen.de/

Further questions? We are happy to receive your email or phone call!

TUM seeks to increase the portion of female employees. Qualified females are, therefore, explicitly encouraged to apply. Severely disabled persons with essentially comparable qualifications will be preferentially hired.

Data Protection Information:
When you apply for a position with the Technical University of Munich (TUM), you are submitting personal information. With regard to personal information, please take note of the Datenschutzhinweise gemäß Art. 13 Datenschutz-Grundverordnung (DSGVO) zur Erhebung und Verarbeitung von personenbezogenen Daten im Rahmen Ihrer Bewerbung. (data protection information on collecting and processing personal data contained in your application in accordance with Art. 13 of the General Data Protection Regulation (GDPR)). By submitting your application, you confirm that you have acknowledged the above data protection information of TUM.

Kontakt: Dr. Hannelore Meyer, +49 15203112080, [email protected], http://www.mikrobio.med.tu-muenchen.de/