Postdoctoral Fellow (m/f/d)

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21009
Postdoctoral Fellow (m/f/d)
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Starting date 01.04.2024 at Cardiology Department, Innere Med III.

A new opportunity for talented and motivated researcher to work as a Postdoctoral Fellow in the research group of Dr. Manju Kumari from Department of Cardiology on DFG funded project entitled ‘Transcriptional control of cardiac function and bioenergetics regulatory circuits by type I interferon signaling’. Despite a well-known role for interferon signaling in controlling immune-metabolism in the state of obesity in mice and humans, little is known about its role in heart failure. This project aims to unravel its role in cardiomyopathy progression. Utilizing excellent transgenic mouse models, primary cell-culture models and the most recent research technologies for big data analysis we will decipher the immune and metabolic network altered in cardiac disorders. The candidate will have the opportunity to apply for grants supporting their further research work to enhance career prospects. Our research group is a diverse interdisciplinary team and the candidate should be able to work independently, having troubleshooting and multitasking skills and capable of intellectual input for project development. Application must include a motivation letter, CV, publication list and at least two reference letters or contact details of the referees.                                                                                                                          

• Job-ID: V000012252
• Field of application: Klinik für Kardiologie, Angiologie und Pneumologie
• Location: Heidelberg
• Start date: 01.04.2024
• Job Category: Science and teaching
• Working hours: full-time
• Published: 08.02.2024
• Limitation:Temporary (30 months, / extension is sought)
• Contract:TV-L

Your Tasks

• To identify the transcriptome and epigenome modulated by altered interferon signaling.
• To identify factors regulating immuno-metabolic signaling pathways under pathophysiological conditions in mice and human models.
• To study cell-type specific gain- and loss-of-function to determine cellular and metabolic effects of factors identified above using transgenic mouse models.
• To learn big data analysis.
• To coordinate research projects with other members in the group as and when required.

Your Profile

• PhD in Molecular Biology/ Biochemistry/Cell Biology/ Life Sciences/ related subjects
• Candidate must have experience in molecular cell biology techniques (cloning, transfection, qPCR, IHC, IP, etc.)
• Candidate should have prior expertise or willing to working with mouse models and experience on experimental rodent models of heart failure, inflammation and obesity
• Hands-on experience in primary cell culture
• Excellent communication and organizational skills with good knowledge of English

What we offer

• Goal-oriented, individual training and development opportunities (e.g. Learning sequencing data analysis)
• Working with the latest techniques / technical equipment Microscopy and Flow cytometry
• Regular team meetings
• Interdisciplinary cooperation with DKFZ for Metabolomics studies
• Possibility to publish scientifically is offered and supported
• Collectively agreed remuneration, attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers

Contact & Application

For further information please contact Manju Kumari  via e-mail or phone.

Interested?

Applications will be accepted until 12.02.2024 via e-mail.

Klinik für Kardiologie, Angiologie und Pneumologie
Manju Kumari, Junior Group Leader
Im Neuenheimer Feld 350
69120 Heidelberg
+49-6221-56-310561
[email protected]

Please note that the UKHD is subject to the provisions of the "Infektionsschutzgesetz". Therefore, valid proof of measles immunity is required for all persons employed at the UKHD.

We stand for equal opportunities. Severely disabled persons are given priority in the case of equal suitability. The University Hospital aims to generally increase the proportion of women in all areas and positions in which women are underrepresented. Qualified women are therefore particularly encouraged to apply. Full-time positions are generally divisible, unless there are official or legal reasons to the contrary.

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21009