Postdoc - Molecular Biology Research in DLBCL (m/w/d)

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21087
Postdoc - Molecular Biology Research in DLBCL (m/w/d)
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wanted for the next possible date in the research group of Dr. Michael Hoetker.

The Hoetker lab at the University Hospital Heidelberg focuses on the corruption of cellular identity in diffuse large B cell lymphoma (DLBCL). We aim to decode epigenetic principles of disease, in particular targeting enhancers and other regulatory elements. The final aim of our studies is to translate the experimental findings into novel treatment strategies for patients at diagnosis and relapse.

The Department of Internal Medicine V of Heidelberg University Hospital is a leading center for research in Hematology and Oncology and provides numerous training opportunities with access to cutting-edge techniques. The location of Heidelberg offers state-of-the-art infrastructure in a highly collaborative environment (NCT, DKFZ and EMBL Heidelberg).

• Job-ID: V000012288
• Field of application: Klinik für Hämatologie, Onkologie und Rheumatologie
• Location: Heidelberg
• Start date: as of now
• Job Category: Science and teaching
• Working hours: full-time
• Published: 14.03.2024
• Limitation:Temporary (24 months, extension is sought)
• Contract:TV-L

Your Tasks

• The postdoctoral fellow will work in a team of enthusiastic biologists and medical scientists with the aim to uncover epigenetic mechanisms of lymphomagenesis as well as therapy resistance and relapse, and to target the non-coding genome as a new therapeutic avenue for DLBCL
• Focus on chromatin biology, 3D genome topology, and its interplay with transcriptional dysregulation in cancer
• Single-cell and bulk epigenetic sequencing approaches in primary patient samples
• Responsible for planning and performing of experiments in the framework of the scientific project plan
• Preparation and presentation of project reports and publications

Your Profile

• MD or PhD in biology, biochemistry or equivalent
• Broad expertise in molecular biology (Western blotting, immunoprecipitations, epigenetic assays, gene expression analysis, cloning, cell culture, lentiviral transductions, flow cytometry, microscopy etc.), experience in NGS techniques and analysis, CRISPR-based epigenetic editing and genome editing techniques
• Experience in writing scientific reports and papers
• Very good knowledge of and experience with MS office, graphic programs, statistical software, bioinformatics tools and online tools (e.g. Illustrator, ImageJ, GraphPad Prism, R, BLAST)
• Fluent both in written and spoken English language

We offer

• Collectively agreed remuneration, attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers
• Goal-oriented, individual training and development opportunities
• Working with the latest techniques / technical equipment
• Possibility of mobile working
• Flexible working hours within the framework of flexitime
• Possibility of habilitation
• Possibility to publish scientifically is offered and supported
• Regular team meetings
• Interdisciplinary cooperation with specialists

Contact & Application

For further information please contact Dr. Michael Hoetker via e-mail [email protected] or phone.

Interested?

We are looking forward to receiving your application. 

Klinik für Hämatologie, Onkologie und Rheumatologie
Dr. Michael Hoetker, head of group
Im Neuenheimer Feld 410
69120 Heidelberg
phone: 06221 56 6435
[email protected]

Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.

The UKHD embraces diversity and values diversity.

Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.

Apply online now: https://karriere.klinikum.uni-heidelberg.de/index.php?ac=application&jobad_id=21087