Postdoc in Computational Genomics – Machine Learning for Multi-Omics Profiling of Cancer Evolution

About the German Cancer Research Center (DKFZ)

The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) is Germany’s largest biomedical research institute and a member of the Helmholtz Association of German Research Centers . Over 3,200 staff members from 88 nations are dedicated to performing and driving cutting edge research for a life without cancer. Organized in more than 100 divisions and research groups, the focus of our 1,400 scientists is to unravel the causes and mechanisms of cancer development and progression, and to develop novel strategies for the diagnosis, early detection, prevention and treatment of cancer though innovative translational research.

Scientists at the DKFZ have received the most prestigious academic awards, including Prof. Harald zur Hausen , awarded the Nobel Prize in Physiology or Medicine in 2008 for his pioneering work on Human Papilloma Viruses (HPV),and Prof. Stefan Hell , who received the Nobel Prize in Chemistry for his research on super-resolution imaging.

The DKFZ core site is located in Heidelberg , the “City of Science ”, which is considered one of the most beautiful cities in Germany with a highly international community: An estimated 56,000 of Heidelberg’s 160,000 inhabitants have an international background – many of whom are scientists or students.

Research Topics and Scientific Collaborations

The DKFZ is an international leader in a number of research areas including stem cell research, bioinformatics and systems biology, cancer genomics, neurooncology, pediatric oncology, cancer prevention, tumor immunology, virology, radiooncology and medical image analysis. The interdisciplinary and collaborative research environment at the DKFZ also results in excellent opportunities for computational and data scientists with interest in biomedical applications.

Research at the DKFZ is organized into six research programs :

On the mission for a life without cancer, the DKFZ collaborates with renowned clinical and research institutions at the local, national and international level . A key goal is to continuously strengthen translational research activities with the aim of sustainably advancing state-of-the-art clinical cancer research in Germany and thereby improving the treatment outcomes and quality of life of cancer patients. Together with University Hospital partners across Germany, the DKFZ established the National Centers for Tumor Diseases (NCT) as leading Comprehensive Cancer Centers in Germany, as well as the Hopp Childrens’ Tumor Center (KiTZ) in Heidelberg with a specific focus on pediatric oncology. Within the German Cancer Consortium for Translational Cancer Research (DKTK) , research institutions and university hospitals at eight partner locations collaborate with the DKFZ, the core center of the DKTK, to speed up the transfer of successful cancer research into clinical practice. Furthermore, the HI-TRON in Mainz is a cooperative effort to make full use of the potential of individualized immunotherapy.

Training Programs and Career Development

Talent management and career development are central parts of DKFZ’s mission to maintain scientific excellence. The DKFZ places strong emphasis on the international recruitment and comprehensive training of excellent scientists, specifically welcoming diverse and international backgrounds.

Dedicated programs train young scientists and clinicians and prepare them for their next career step:

The DKFZ has developed programs to support the reconciliation of family and careers at all levels and international employees are supported by the International Staff Services in the planning, preparation and realization of their stay in Heidelberg.

Innovation Management

The DKFZ builds on strong Innovation Management to foster the development of innovative preventive, diagnostic and therapeutic products for maximum societal benefit. It facilitates technology transfer through licensing and support of spin-off companies. Recent examples include iOmx Therapeutics , Apogenix and mtm laboratories. The DKFZ also has strong collaborations with industry partners, such as Bayer Healthcare , Bosch , SAP and Siemens .