Postdoc – Epigenetic-Metabolism axis in metabolic disease (m/f/x)

Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.

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The Helmholtz Institute for Metabolic, Obesity and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) at the University of Leipzig, aims at uncovering the molecular underpinnings of metabolic, obesity and vascular disorders to enable precision therapies. HI-MAG is part of Helmholtz Center Munich. As one of the world’s leading research institutes, Helmholtz Center Munich is a highly driven and stimulating international environment. Together with renowned scientists and supported by state-of-the-art infrastructure, you will have the opportunity to make important contributions towards scientific knowledge and the improvement of people’s quality of life.

The YIG "Vascular Epigenetics", headed by Dr. Bilal Sheikh , elucidates the molecular mechanisms that underpin the complex interplay between metabolic, lifestyle and epigenetic factors. The group focuses on these themes in the context of metabolic disease.

The ultimate aim of the current project is to establish novel therapies for the treatment of metabolic dieases such as obesity, diabetes and fatty liver disease. For this project, based in Leipzig, we are now recruiting a

Your responsibilities

• Establishing primary human cell cultures
  
• Transcriptomic (RNA-seq), epigenetic (ChIP-seq) and metabolomics (mass spectrometry) sample preparation and processing
  
• Basic bioinformatics analysis
  
• Analysis of pre-clinical animal models
  

Your qualifications

• PhD in the life sciences, with a background in molecular biology and epigenetics
  
• Excellent publication record with at least one first author paper in an internationally reputable journal
  
• Extensive experience in cell culture of primary cells
  
• Highly motivated and creative, with strong communication skills
  
• Excellent command of written and spoken English
  

Desirable qualifications

• Basic knowledge of bioinformatics pipelines (R, Galaxy)
  
• Background in metabolomics
  

The Helmholtz Center Munich offers a world-class, international and highly collaborative environment with extensive scientific resources. We provide you with a challenging and versatile workplace, allowing you the freedom to follow your instincts and be creative. With state-of-the-art infrastructure and personalized career-support, we prioritize your development and help you achieve your career goals.

To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.

The position is initially offered for one year with the possibility of an extension based on performance.

Curious?
If you have further questions, please contact Dr. Bilal Sheikh, [email protected]. 

Your application should include:
• Full curriculum vitae
• A cover letter covering research experience and future research interests
• List of publications
• At least 2 reference letters

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung (HI-MAG)
Philipp-Rosenthal-Str. 27

04103 Leipzig