PostDoc (f/m/d)

The Institute for Cardiovascular Physiology, University Medical Center Göttingen opens a position as:

• Specialization: in Cardiovascular Physiology
• Limitation: available for 2 years and further extension ist anticipated
• Working period: full time (38,5h / week)
• Tariff: salary according to TV-L
• Announcement published on 06.06.2023
• Vacancy from 01.09.2023
• Application deadline: 07.07.2023

About us:

Heart failure is one of the most common causes of morbidity and mortality worldwide. At the cell level, the injured heart reacts with complex and stereotypical remodeling processes in cardiomyocytes and in the so-called non-cardiomyocytes (fibroblasts, endothelial cells, immune cells, etc.). Striking changes in these cells are redox-dependent modifications to regulatory proteins. An imbalance in the production of reactive oxygen species and an altered "redox state" is involved in many cardiac stress reactions that are involved in the development of heart failure. As part of our projects, we develop technical tools for the quantification of redox changes in cardiomyocytes and non-cardiomyocytes and their consequences for the function at cell and organ level (see for example doi.org/10.1038/s41467-023-37744-x).

Your tasks:

• Driving experimental projects that study redox modifications in genetically modified induced pluripotent derived cardiomyocytes
• Apply genetically encoded biosensors
• Apply redox proteomics methods and analyze proteomics data sets
• Analyze the consequences of redox modifications for cardiomyocyte physiology (force of contraction etc.)
• Collaborative work in our research team, for example together with PhD or BSc/MSc students
• Teaching of undergraduate students in physiology as part of the study programmes human medicine, dental medicine, molecular medicine and cardiovascular physiology

Your profile:

• Enthusiasm for science and interest in understanding redox biology
• BSc/MSc degree and PhD in physiology, molecular or cell biology, biochemistry or a related subject
• Experience with analyzing protein modifications and analyzing proteome data sets
• Experience with analyzing cardiomyocyte physiology
• Ability to work independently and also in a team
• Good command of the English language and basic knowledge in German language

Our offer:

• Work in a stimulating, interdisciplinary and innovative environment within a highly motivated, skilled and international team
• Salary according to the collective agreement for the public State service (TV-L) including social benefits

Please send the PDF file of your application including your CV, exam certificates and list of publications, a summary of your current scientific work and names of three academic referees by e-mail.

The University Medical Center Göttingen is committed to professional equality. We therefore seek to increase the proportion of under-represented genders. Applicants with disabilities and equal qualifications will be given preferential treatment.

We look forward to receiving your application by 07.07.2023:

Please send your application only via e-mail as a PDF-file.

Travel and application fees cannot be refunded or transferred.

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