Computational Postdoctoral Fellow/ Computer Scientist / Bioinformatician

23 Jan 2024
Job Information

Organisation/Company

European Molecular Biology Laboratory

Research Field

Biological sciences

Researcher Profile

Recognised Researcher (R2)

Country

Germany

Application Deadline

16 Feb 2024 - 23:00 (UTC)

Type of Contract

To be defined

Job Status

Full-time

Hours Per Week

To be defined

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Furlong lab at EMBL Heidelberg combines genomics, genetics and computational biology to obtain a functional understanding of how our genome is regulated. We combine interdisciplinary approaches, including single cell genomics, chromatin conformation capture approaches, and imaging with computational methods such as machine learning, to uncover general principles of genome regulation. The interdisciplinary and international team combines both experimental and computational (wet and dry) approaches, and is a highly collaborative environment to perform cutting-edge research.

We are looking for a highly motivated computational biologist/bioinformatician (either post-doc or staff position) to collaborate within the team in diverse projects. You will work on diverse types of NGS data, collaborating with experimental and computational biologists in a dynamic, open and creative culture. The successful candidate will lead data analyses to examine different aspects of genome regulation, such as large-scale chromatin conformation capture data in different conditions, including mutants, to undercover 3D principles of how enhancers interact with their target gene’s promoters. A second direction involves extensive single cell data of different modalities across different conditions.

Your role
As part of the research team, you will participate in multiple projects and develop your own project in collaboration with lab members, and shape your research profile in several of the following areas:

Conduct integrative data analysis for biological discoveryChromatin conformation capture data at large-scale
Single-cell ATAC and RNA-seq data analysis at ultra-large scale
Mutant and natural sequence variation data
Develop pipelines that other lab members can use
Model the impact of perturbations on 3D chromatin interactions
Discern the relationship between chromatin state and gene expression
Model cell states, transitions and genetic dependencies 
 
You have
A PhD in computer science, bioinformatics or an equivalent related field
Extensive experience with large-scale NGS data analyses
Intermediate-to-high level skills in R and Python programming are required
Experience with workflow management systems (e.g. Snakemake) and cluster computing environments (e.g. SLURM) are highly desired
Excellent organizational skills and enjoy working in an independent and proactive manner in a highly motivated, collegial international scientific environment
Ability to present and visualise results in an intuitive manner e.g. Rmarkdown
Interests in computational algorithms, sequence alignments and biological discovery are a plus.
 
You might also have
You are self-motivated and excited by contributing to biological discoveries, you are interested in interdisciplinary cuting-edge science, enjoy collaborative work and like to communicate concepts and results and brain-storm with colleagues. 
 
Why join us
This is a great opportunity to develop expertise in the analyses of diverse types of state-of-the-art omics data and methods of data integration and modeling. You will be a crucial part of biological discovery in diverse areas of genome regulation, cell fate decisions, and development. You will be part of a very interactive, collaborative and inter-cultural team.

EMBL offers attractive conditions and benefits appropriate to an international research organisation with a very collegial and family-friendly working environment. Competitive salary and social security benefits, financial support for relocation, a relaxed culture, professional development, an on-site nursery, canteen and other staff facilities make EMBL a great place to work.

** Don’t meet every single requirement? We are dedicated to building a diverse, inclusive and authentic workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.
 
What else you need to know
We are Europe’s research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1900 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research. The working language of the institute is English.

In your online application, you will be asked to include a cover letter, CV and the contact details of 3 referees. 

EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here.

Requirements
Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

European Molecular Biology Laboratory

Country

Germany

Geofield

Where to apply

Website

https://jobrxiv.org/job/european-molecular-biology-laboratory-27778-computation…

Contact

Website

https://www.embl.org/

STATUS: EXPIRED