Search position : Controlled "Hot Nano-SPots" ThroUgh NanopaRticle-Assisted Heating and Luminescent Thermometry

26 Mar 2024
Job Information

Organisation/Company

Universite de Montpellier

Department

Human Resources

Research Field

Chemistry

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

1 May 2024 - 23:59 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

38

Offer Starting Date

1 Sep 2024

Is the job funded through the EU Research Framework Programme?

HE

Reference Number

2024-R0224

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

We propose a conceptually new approach to the NP-assisted heating/hyperthermia based on a deep understanding of a heat transfer at nanoscale and a precise temperature readout permitting to optimized and controlled “hot spots” effect triggered by magnetic field or light irradiation, which will be more efficient than macroscopic heating of the whole solution due to its very localized character.

Main mission and activities:

i) design heater@thermometer NP by using Fe3O4 NP as nanoheater core enwrapped by silica shell of different thickness containing emissive temperature sensors: sensor 1 integrated in the silica pores to give the readout of the surface temperature and sensor 2 attached on the surface at fixed distance to measure the temperature at the nanoscale distance from the surface.

(ii) to demonstrate the “hot spot” effect through the measurements of temperatures, under external activation (light irradiation or magnetic field) in the shell and at a fixed nanoscale distance from the NP’ surface.

(iii) to demonstrate the “hot spot” hyperthermia with intracellular thermometry on cancer cells.

 

Synthesis of core@shell inorganic nanoparticles. Synthesis of lanthanide based clusters. Encapsulation of lanthanide-based clusters and surface functionalisation of the as-obtained nanoparticles. Conduct experiments of temperature measurements under external stimuli.

Requirements

Research Field

Chemistry

Education Level

PhD or equivalent

Skills/Qualifications

Applicants must hold a PhD with a background in inorganic/organometallic/coordination chemistry, along with knowledge and experience in luminescence spectra measurements and interpretation of lanthanides materials, are encouraged to apply. Prospective candidates should possess strong analytical and experimental skills, as well as a keen interest in interdisciplinary research at the intersection of chemistry and materials science.

Research Field

Chemistry

Additional Information
Eligibility criteria

Applicants must hold a PhD with a background in inorganic/organometallic/coordination chemistry.

Selection process

Send your CV and cover letter by email at : [email protected] and [email protected] before 1st of may of 2024.

Work Location(s)

Number of offers available

1

Company/Institute

Institut Charles Gerhardt Montpellier (ICGM)

Country

France

City

Montpellier

Postal Code

34090

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Montpellier

Website

http://www.umontpellier.fr/

Street

163 rue Auguste Broussonnet

Postal Code

34000

E-Mail

[email protected]
[email protected]

STATUS: EXPIRED