Postdoctoral Researcher M/W in Organic Chemistry: Design of photo-immolable nanomaterials

Updated: 4 months ago
Location: Pessac, AQUITAINE
Job Type: FullTime
Deadline: 01 Feb 2024

13 Jan 2024
Job Information
Organisation/Company

CNRS
Department

Chimie et Biologie des Membranes et des Nanoobjets
Research Field

Chemistry
Environmental science
Researcher Profile

First Stage Researcher (R1)
Country

France
Application Deadline

1 Feb 2024 - 23:59 (UTC)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

35
Offer Starting Date

1 Apr 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The final goal of this research project is to develop self-immolable nanomaterials by light stimulation. During the current 1st phase of this project, the recruited postdoctoral fellow will synthesize model scaffolds that are suitable for such photodegradable reactions. This will involve the association of fragmentation reactions with specific photo-induced leaving groups. A methodological approach will be used in order to identify the optimum conditions necessary for such a reactivity pattern.
The identification of a light-induced self-degradable chemical pattern during this phase of the project will allow its future incorporation: (1) in polymers, for the design of new generations of light-degradable materials and (2) in phospholipids, for the design of stimuli-controlled drug-delivery systems.

- multi-step organic synthesis (Michel additions, heterocyclic chemistry, organometallic chemistry, orthogonal protective groups, fluorophores, etc.)
- analytical characterization of the synthesized chemicals: NMR, MS, IR, UV/Vis, Fluorescence spectroscopy, HPLC)
- bibliography
- regular reports and work-in-progress meetings in English
- article writing

This project is financially supported by the Emergence Call 2024 of the National Institute of Chemistry (INC) – CNRS, France.

Host institution: CBMN (Institute of Chemistry and Biology of Membranes and Nano objects) in Bordeaux, web: http://www.cbmn.u-bordeaux.fr
Team: MMB (Molecular Modeling and Bioengineering), supervisor Dr. Edouard Badarau, web: http://www.cbmn.u-bordeaux.fr/28-chimie-biophysique-modelisation-de-bio…

Working place: Bordeaux – France


Requirements
Research Field
Chemistry
Education Level
PhD or equivalent

Research Field
Environmental science
Education Level
PhD or equivalent

Languages
FRENCH
Level
Basic

Research Field
Chemistry
Years of Research Experience
None

Research Field
Environmental science
Years of Research Experience
None

Additional Information
Eligibility criteria

- organic chemistry: multistep chemistry under inert/moisture/light-protected conditions on a scale of 50mg to 50g
- analytical chemistry: NMR, MS, IR, UV/Vis, FS, HPLC
- photochemistry: recommended but not mandatory
- previous supervision of M2 students
- professional English necessary to work in an international environment
- participation to regular routines in an organic chemistry lab (stock management, chemical ordering, waste management, etc.)


Additional comments

-


Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR5248-EDOBAD-001/Default.aspx

Work Location(s)
Number of offers available
1
Company/Institute
Chimie et Biologie des Membranes et des Nanoobjets
Country
France
City
PESSAC
Geofield


Where to apply
Website

https://emploi.cnrs.fr/Candidat/Offre/UMR5248-EDOBAD-001/Candidater.aspx

Contact
City

PESSAC
Website

http://www.cbmn.u-bordeaux.fr/

STATUS: EXPIRED

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