29 Mar 2024
Job Information
- Organisation/Company
CNRS- Department
Institut Interdisciplinaire de Neurosciences- Research Field
Neurosciences
Biological sciences- Researcher Profile
First Stage Researcher (R1)- Country
France- Application Deadline
17 Apr 2024 - 23:59 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
35- Offer Starting Date
15 May 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The project aims to develop new molecular probes that will enable endogenous proteins to be studied and monitored directly in their native cellular environment. Protein engineering methods will then be used to generate probes from these specific molecular recognition modules that will be used in different but complementary imaging modalities, ranging from super-resolution fluorescence microscopies to single protein tracking techniques via cryo-electron microscopy.
We are looking for a highly motivated postdoctoral researcher to develop new tools for studying endogenous molecules in their cellular context. These tools will be designed to image the same protein complex with both fluorescence microscopy and (cryo-)electron microscopy, revealing their ultrastructural organization and understanding their functions.
Apply directed evolution to generate new binders
Characterize new binders using biophysical and biochemical methods
Design binders for use as imaging tools
Characterize imaging tools in various cellular contexts (adherent cells, macrophages, neurons, cancer cells)
Imaging molecular organization and dynamics in subcellular structures
Develop cryo-electron microscopy approaches in cells
Created in 2011, IINS brings together 180 scientists from different nationalities and backgrounds (chemistry, structural biology, molecular and cell biology, biophysics, clinical medicine, advanced imaging, neurobiology) to understand brain function in healthy and pathological states. IINS conducts multidisciplinary research at the cutting edge of synapse biology and neural systems physiology, with a particular focus on the development of new technologies and tools.
Requirements
- Research Field
- Neurosciences
- Education Level
- PhD or equivalent
- Research Field
- Biological sciences
- Education Level
- PhD or equivalent
- Languages
- FRENCH
- Level
- Basic
- Research Field
- Neurosciences
- Years of Research Experience
- None
- Research Field
- Biological sciences
- Years of Research Experience
- None
Additional Information
Eligibility criteria
Skills in biotechnology, protein engineering and/or cell imaging
- Website for additional job details
https://emploi.cnrs.fr/Offres/CDD/UMR5297-MELDES0-205/Default.aspx
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Institut Interdisciplinaire de Neurosciences
- Country
- France
- City
- BORDEAUX
- Geofield
Where to apply
- Website
https://emploi.cnrs.fr/Candidat/Offre/UMR5297-MELDES0-205/Candidater.aspx
Contact
- City
BORDEAUX- Website
http://www.iins.u-bordeaux.fr/?lang=en
STATUS: EXPIRED
Similar Positions
-
Post Doctoral Researcher Position At The Biology Of Spirochetes Unit, Department Of Microbiology, Institut Pasteur In Paris, Institut Pasteur, France, about 23 hours ago
https://research.pasteur.fr/en/team/biology-of-spirochetes/ Dive into the Fascinating World of Spirochetes ! Do you want to contribute to a project aiming at understanding what makes Leptospira ha...
-
Postdoctoral Position In Computer Aided Drug Design, Institut Pasteur, France, about 23 hours ago
A 30-month postdoctoral position in Computer-Aided Drug Design is available at Institut Pasteur in Paris within the Chemoinformatics and Proteochemometrics group of Olivier Sperandio and the Struc...
-
Postdoctoral Position In Evolutionary Genomics Of Mobile Genetic Elements And Antibiotic Resistance , Institut Pasteur, France, 8 days ago
The Microbial Evolutionary Genomics unit (head Eduardo Rocha) at the Institut Pasteur in Paris (CNRS UMR3525) is inviting applications for a postdoctoral position in comparative genomics, computa...
-
Research Engineer Or Postdoctoral Position In Biostatistics Or Bioinformatics, Institut Pasteur, France, about 23 hours ago
We are currently seeking to recruit a post-doctoral researcher at the Institut Pasteur Unit “Epidemiology and Modeling of bacterial Evasion to Antibacterials” (director, Didier Guillemot) which is...