Postdoctoral Researcher in Biochemistry and Protein NMR (M/F)

Updated: 3 months ago
Location: Grenoble, RHONE ALPES
Job Type: FullTime
Deadline: 04 Mar 2024

13 Jan 2024
Job Information
Organisation/Company

CNRS
Department

Institut de biologie structurale
Research Field

Chemistry
Biological sciences
Pharmacological sciences
Researcher Profile

Recognised Researcher (R2)
Country

France
Application Deadline

4 Mar 2024 - 00:00 (UTC)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

35
Offer Starting Date

1 Jun 2024
Is the job funded through the EU Research Framework Programme?

HE / ERC
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The successful candidate will work on the development of innovative isotope labelling methods to push the biological applications of NMR beyond their current limits, and will apply the new methods to the study of large molecular complexes and machines of medical importance, as part of the European ERC advanced grant XXL-NMR project.

- Development of isotope labelling protocols
- Cell-free expression of proteins and purification for NMR studies
- NMR characterization of large complexes
- Functional studies of large proteins complexes
- Co-supervision of students
- Publications writing
- Taking part in the life of the research group (contributing to logistics, monitoring stocks of reagents, etc.)

Located on the Grenoble science campus (ESRF/ILL/EMBL/IBS), the structural biology institute (IBS) is a leading national and international research institute in the field of integrated structural biology. The IBS is a research center, a technical infrastructure, a host site and a scientific training center. Its mission is to develop research in structural biology, a crucial field for understanding fundamental biological mechanisms. It is supported by 12 state-of-the-art facilities, including high field NMR facility equipped with 950, 850, 700 and 600 MHz NMR spectrometers, wet-lab facilities dedicated to in vivo and in vitro protein expression and purification, and state-of-the-art imaging and biophysics facilities for sample characterization.
joint research unit (CEA-CNRS-UGA), the IBS is made up of 21 research groups, each offering a multidisciplinary approach at the frontiers of biology, physics and chemistry, in line with the IBS's 3 main lines of research. Nearly 300 people work at IBS as researchers, post-docs, PhD students, engineers and technicians in a multicultural and international environment.

The postdoctoral researcher recruited will join the NMR of Large Assemblies group, which develops and applies advanced isotope labelling and NMR methods to study the structure, dynamics and mechanisms of large protein complexes. The group headed by Dr. Boisbouvier comprises a research director, three engineers, two post-docs and two PhD students.


Requirements
Research Field
Chemistry
Education Level
PhD or equivalent

Research Field
Biological sciences
Education Level
PhD or equivalent

Research Field
Pharmacological sciences
Education Level
PhD or equivalent

Languages
FRENCH
Level
Basic

Research Field
Chemistry
Years of Research Experience
1 - 4

Research Field
Biological sciences
Years of Research Experience
1 - 4

Research Field
Pharmacological sciences
Years of Research Experience
1 - 4

Additional Information
Eligibility criteria

- Candidates must hold a PhD in chemistry, biochemistry or structural biology (or a related discipline) and have experience of protein expression and purification as well as experience or interest in solution NMR spectroscopy.
- Ability to conceptualise, creativity, scientific curiosity, sense of innovation.
- Good communication (written/oral) and teaching skills.
- Team spirit.
- C2 level English (written/oral)


Additional comments

The post can be extended for up to five years and is funded by the European Research Council under the European ERC advanced grant XXL-NMR programme. This post is ideal for young post-docs who wish to gradually develop independent research and apply for a permanent research post in France.

The indicated experience is 1 to 4 years, but the profile is also open to candidates with more experience (up to 10 years).


Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR5075-VALLAN-019/Default.aspx

Work Location(s)
Number of offers available
1
Company/Institute
Institut de biologie structurale
Country
France
City
GRENOBLE
Geofield


Where to apply
Website

https://emploi.cnrs.fr/Candidat/Offre/UMR5075-VALLAN-019/Candidater.aspx

Contact
City

GRENOBLE
Website

http://www.ibs.fr/

STATUS: EXPIRED

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