The candidates will develop innovative, high-throughput cell and organ electric stimulation setups to investigate how membrane potential, static and time-variable electric fields impact biological fate or 3D scaffolds consisting of defined out-of-plane curvatures. Biological systems of interest include embryonic or adult intestine, isolated intestinal mesenchymal cells, epithelial cells, tumour cells from human colonic carcinoma and from stromal gastro-intestinal tumors. The systems will be characterized in terms of membrane potential (voltage-sensitive dyes, calcium imaging, electrophysiology), differentiation (immunohistochemistry, RNAseq, proteomics), migration (live 2D or 3D confocal imaging), proliferation, metabolism (Seahorse methodology). A microfabrication facility will also allow to examine how 2D or 3D topographic or mechanical cues interact with bioelectrical or metabolic properties.
The candidates will:
- Plan, direct and conduct advanced research experiments, evaluate and analyze data
- Summarize research findings and publish results in international scientific journals
- Supervise interns and be responsible for laboratory operations
- Write or assist in writing research projects
The candidates will benefit from the scientifically rich environment of the Labex, comprising
specialists in biophysics, embryology, cell biology and metabolism.
Similar Positions
-
Postdoctoral Fellowships Metabolic Control Of Cell Growth And Senescence, Nature Careers, France, 26 days ago
Two Postdoctoral positions are available in the team Cell Growth Control by Nutrients (Nature Metabolism, 6, 323; Nature Cell Biology, 7, 286; Cell Metabolism, 5, 476; J. Exp. Med., 211, 2249; EMB...
-
Expression Of Interest – Marie Skłodowska Curie Actions – Postdoctoral Fellowships 2024 (Msca Pf), Nature Careers, France, 21 days ago
The Marie Skłodowska Curie Postdoctoral Fellowship programme (MSCA-PF) is a highly renowned European funding scheme. It offers talented scientists the unique chance to set up 2-year research and ...