Postdoc on massive diversity generation: from evolution to design (M/F)

Updated: 23 days ago
Location: Paris 05, LE DE FRANCE
Job Type: FullTime
Deadline: 25 Apr 2024

5 Apr 2024
Job Information
Organisation/Company

CNRS
Department

Laboratoire de physique de l'ENS
Research Field

Physics
Researcher Profile

First Stage Researcher (R1)
Country

France
Application Deadline

25 Apr 2024 - 23:59 (UTC)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

35
Offer Starting Date

1 Sep 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The aim of this postdoc is to computationally understand and model the efficiency of the Diversity Generating Retroelements (DGR) system used by phages and certain bacteria to diversify their proteins. This theoretical understanding will then be used in collaboration with David Bikard's group (Institut Pasteur) to generate new variants of the Cas9 protein.

The postdoc, based at LPENS, will be responsible for developing models based on sequence data and mutation probabilities performed by the DGR retropolymerase system to find the best DNA sequences for generating new proteins. He/she will work closely with the Institut Pasteur experimental group.

The young researcher will work at LPENS, and will frequently visit the Institut Pasteur.


Requirements
Research Field
Physics
Education Level
PhD or equivalent

Languages
FRENCH
Level
Basic

Research Field
Physics
Years of Research Experience
None

Additional Information
Eligibility criteria

- advanced level in statistical physics/out-of-equilibrium processes
- basic knowledges in bioinformatics


Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR8023-REMMON0-009/Default.aspx

Work Location(s)
Number of offers available
1
Company/Institute
Laboratoire de physique de l'ENS
Country
France
City
PARIS 05
Geofield


Where to apply
Website

https://emploi.cnrs.fr/Candidat/Offre/UMR8023-REMMON0-009/Candidater.aspx

Contact
City

PARIS 05

STATUS: EXPIRED

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