Postdoc in inflammation /regeneration

5 Apr 2024
Job Information

Organisation/Company

Institut Pasteur

Department

Immunology

Research Field

Biological sciences » Biology

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

17 May 2024 - 17:00 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Offer Starting Date

1 Jul 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Our laboratory has one position available for postdoctoral fellow in the area of inflammation and regenerative disease research. We are interested in mechanisms of tissue homeostasis, adaptation and repair, with an emphasis on tissue long lived cells such as stromal cells, and their crosstalk with immune cells, stem cells and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using these approaches, we previously identified an essential role for specific subsets of stromal cells in tissue homeostasis/repair, vascular remodeling and antitumor immunity (Dulauroy et al., Nature Medicine 2012; Stzepourginski et al., PNAS 2017; Jacob et al., Cell Stem Cell 2022; Di Carlo et al., Nature Immunology 2023). Building on these findings, this project aims at identifying novel mechanisms regulating tissue repair and inflammation, with a focus on stromal immunoregulation and plasticity in organs with high remodeling capacity such as the skin, skeletal muscle or adipose tissue.

For more information and to apply, send a motivation letter, CV and contact information for 2 references to Lucie Peduto ([email protected] ).

Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Skills/Qualifications

Required qualifications: A recent PhD or MD/PhD degree in immunology, vascular biology or related biomedical field, with a track record of publications and lab experience in one or more areas that include: vascular biology, innate immunity, stromal/mesenchymal stem cells, tissue repair. Highly motivated candidates with experience in murine models and transcriptomics, and interest in immune-stroma interaction and immunoregulation are strongly encouraged to apply.

Specific Requirements

Specific requirements:

• Required : Solid experience with in vivo rodent models and flow cytometry
• Desirable : Previous experience in transcriptomics analysis (scRNAseq), mice models for disease (skin, skeletal muscle, obesity)
• Would be a plus : Previous experience in scripting languages (R) and Seurat.

Languages

ENGLISH

Level

Good

Research Field

Biological sciences

Years of Research Experience

1 - 4

Additional Information
Benefits

Benefits include comprehensive healthcare coverage and 6 weeks paid annual leave. Research will be conducted at Institut Pasteur in the center of Paris, which contains state of-the-art facilities and a highly collaborative research environment with 13 Departments across Biology/Physics/Biomedical fields. Our lab is co-affiliated with the Departments of “Immunology” and “Developmental and Stem Cell Biology”, facilitating interactions and collaborations in these different research areas.

Work Location(s)

Number of offers available

2

Company/Institute

Institut Pasteur

Country

France

City

Paris

Postal Code

75015

Street

25 rue du Docteur Roux

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Paris

Website

https://research.pasteur.fr/en/team/group-lucie-peduto/

Street

25 rue du Docteur Roux

Postal Code

75015

E-Mail

[email protected]

STATUS: EXPIRED