28 Feb 2024
Job Information
- Organisation/Company
Universite de Montpellier- Department
Human Resources- Research Field
Biological sciences » Biology- Researcher Profile
First Stage Researcher (R1)- Country
France- Application Deadline
24 Mar 2024 - 23:59 (Europe/Paris)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
38- Offer Starting Date
1 Apr 2024- Is the job funded through the EU Research Framework Programme?
HE- Reference Number
2024-R0145- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Name of the project: Enrichment of emerging antibiotic resistance of public health concern in the hydric environment: toward a genomic, phenotypic and evolutionary-based proxy of exposition risk in a territory.
The postdoc will work in the context of the WATERISK project, funded by the ExposUM Institute (University of Montpellier). The aim of this project is to identify genomic and phenotypic characteristics determining the enrichment of emerging AMR genes of public health concern in hydric environments. WATERISK focuses on emerging resistances to β- lactams in Gram-negative bacteria and is designed at the local scale (drainage basin of a coastal river and hospitals from the Montpellier area). This project is composed of three main parts: (1) building a resistant isolates collection, (2) obtaining and analysing the genomes of the isolates of the collection and (3) characterizing the phenotype and evolutionary potential of associations of plasmid and strains from the collection.
Main mission and activities:
The postdoc will be in charge of the second part and will conduct the genome sequencing analysis of a collection of 500 Enterobacteriacea isolates collected at Montpellier University Hospitals and at different points along the coastal river. The goal of this analysis will be to identify the association of antibiotic resistance genes with strains, species, mobile genetic elements and other resistance genes across environments to better understand the circulation of antibiotic resistance genes.
The postdoc will also participate in the characterization of the evolutionary potential of strain-plasmid associations by designing and implementing an experimental evolution approach and contributing to the phenotypic and genomic characterization of the evolved lines.
Genomic analysis: de novo genome assembly, annotation, strain identification, antibiotic resistance gene screening, mobile genetic element search.
Large dataset management.
Basic techniques in microbiology.
Experimental evolution.
Articles writing.
Presentation of the results in national and international conferences.
Requirements
- Research Field
- Biological sciences » Biology
- Education Level
- PhD or equivalent
Skills/Qualifications
PhD in evolutionary biology or microbiology / skills in genomics
- Research Field
- Biological sciences » Biology
Additional Information
Eligibility criteria
PhD in evolutionary biology or microbiology
Selection process
Send your CV and cover letter by email to : [email protected] and [email protected]
Additional comments
The postdoc will be based at the Centre for Functional and Evolutionary Ecology (CEFE) in Montpellier, in the Evolutionary Genetics and Ecology team and will work in close interaction with the Physe team (Hydric Pathogens Health and Environment) at the Hydroscience institute in Montpellier.
The CEFE is the largest French laboratory for ecology and evolution. It includes common services in molecular biology and chemistry, as well as several groups dedicated to evolutionary ecology. The Genetics and Evolutionary Ecology team is a very dynamic and stimulating scientific environment, with 11 permanent researchers and 10 to 15 PhD and post-doctoral students.
HydroSciences Montpellier laboratory brings together disciplinary skills to study, quantify and forecast the impacts of climate and human activities on water resources in Mediterranean and tropical regions. Among the main themes studied is the dynamics of emerging contaminants and the health risks and adaptation mechanisms of waterborne pathogenic bacteria.
The postdoc will interact with the researchers and students of the Genetics and Evolutionary Ecology and Physe teams and with the technical staff of the Molecular and Experimental Genetics service (at CEFE).
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Hydrosciences Montpellier
- Country
- France
- City
- Montpellier
- Postal Code
- 34000
- Geofield
Where to apply
[email protected]
Contact
- City
Montpellier- Website
http://www.umontpellier.fr/- Street
163 rue Auguste Broussonnet- Postal Code
34000
[email protected]
[email protected]- Phone
0033 4 67 61 32 11
STATUS: EXPIRED