Post-doctoral researcher in biology (M/F)

8 May 2024
Job Information

Organisation/Company

CNRS

Department

Intégrité du génome, ARN et cancer

Research Field

Biological sciences
Biological sciences » Biology

Researcher Profile

Recognised Researcher (R2)

Country

France

Application Deadline

31 May 2024 - 23:59 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

35

Offer Starting Date

1 Oct 2024

Is the job funded through the EU Research Framework Programme?

HE / ERC

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

As part of a European Research Council (ERC) project, the CNRS is recruiting a full-time post-doctoral researcher in the "Regulation of Microtubule Dynamics by Tubulin Code" team, led by Carsten JANKE, Institut Curie, CNRS UMR3348, to investigate the molecular effects of tubulin code and their impact on functions at the organismal level. The focus of this post-doc will be to study the pathological effects of hyper-polyglutamylation in neurons and in vitro.

Specific activities include carrying out experiments and analysing data, in particular using :
- Molecular biology (cloning, Q-PCR, etc)
- Cell biology (primary culture of neurons, transduction with lentiviruses, marking of endogenous proteins with CRISPR/Cas9, etc)
- Microscopy (live cell imaging, immunolabelling, expansion microscopy, superresolution microscopy, etc)
- Analysis of microscopic images, mounting
- Biochemistry (protein analysis by western blots, proximity ligation tests, etc)
- Animal experimentation (planning mouse crosses for the project, mouse dissection, genotyping, analysis of animals for immunohistochemistry, etc)
The candidate will interact closely with the members of his/her team and the collaborating teams in the network for this ERC project, as well as with the platforms available at the Institut Curie Research Centre.
The candidate will also be involved in the dissemination of project results, through publications, oral presentations and presentations to the general public.

The Controlling microtubule dynamics and function with the tubulin code
team is based at the Institut Curie Research Centre in Orsay (91), within UMR3348 CNRS.

Requirements

Research Field

Biological sciences

Education Level

PhD or equivalent

Research Field

Biological sciences

Education Level

PhD or equivalent

Languages

FRENCH

Level

Basic

Research Field

Biological sciences

Years of Research Experience

1 - 4

Research Field

Biological sciences » Biology

Years of Research Experience

1 - 4

Additional Information
Eligibility criteria

The highly motivated candidate must hold a PhD in cell biology, immunology, biochemistry, molecular biology or a related discipline. Knowledge of animal experimentation (mice), cell biology and microscopy is required, as well as skills in image analysis, molecular biology and biochemistry.
The candidate must be able to work independently to develop innovative ideas, but also to collaborate with other members of the laboratory and the network of teams involved in the ERC, to promote interdisciplinarity. The candidate will have excellent communication skills and a good command of English.

Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR3348-SOPBEI-001/Default.aspx

Work Location(s)

Number of offers available

1

Company/Institute

Intégrité du génome, ARN et cancer

Country

France

City

ORSAY

Geofield

Where to apply

Website

https://emploi.cnrs.fr/Candidat/Offre/UMR3348-SOPBEI-001/Candidater.aspx

Contact

City

ORSAY

STATUS: EXPIRED