Post-doctoral position on R-loop analyses in human cells

26 Mar 2024
Job Information

Organisation/Company

Universite de Montpellier

Department

Human Resources

Research Field

Biological sciences » Biology

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

5 Apr 2024 - 23:59 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

38

Offer Starting Date

1 Jun 2024

Is the job funded through the EU Research Framework Programme?

HE

Reference Number

2024-R0218

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description
The IGMM conducts excellent and innovative fundamental research with potential implications in the biomedical field and molecular and cellular medicine, particularly in treating cancer and certain infectious or genetic diseases. It has a long-standing internationally recognized reputation in the disciplinary fields that constitute its main research axes: RNA Function and Maturation, Gene Regulation and Epigenetics, Tumorigenesis, Cell Cycle and Death, Immunology, Viral Infections, and more recently, Cellular Metabolism. The IGMM is located on the CNRS campus on Route de Mende and shares numerous programs and technological platforms with its neighboring partner institutes, the CRBM and the IRIM. Approximately 200 people work at the IGMM, distributed among 17 research teams, and a joint laboratory with a private company. The IGMM has access to the Montpellier BioCampus platforms, including notably microscopy, genomics, and proteomics facilities. The candidate will be assigned to the team led by D. Libri and O. Porrua, which studies gene expression mechanisms using biochemical, molecular biology, and genomic approaches.
 
Main mission: To adapt the R-loop mapping techniques developed in the yeast model by the host laboratory to the human model
 
Activities:   
- Generate high-resolution maps of R-loops in human cells using immunoprecipitation coupled with high-throughput sequencing techniques. The candidate will perform all steps of these experiments: culturing human cells under study conditions, constructing cDNA libraries for high-throughput sequencing, etc., and will participate in the analysis of sequencing data.
- Analyze R-loops in cells using microscopy techniques (immunofluorescence).
Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Skills/Qualifications

-Skill and rigor in experimental work

- Expertise in common techniques in molecular and cellular biology

- Experience in RNA and R-loop analyses

- Basic understanding of bioinformatics applied to genomics

- Experience in culturing human cells -Organizational skills and proficiency in written and oral English communication (reports, presentations

- PhD required in biological sciences

- Ideally 3 years of post-doctoral experience

Research Field

Biological sciences » Biology

Additional Information
Eligibility criteria

PhD required in biological sciences

Selection process

SEnd your CV and cover letter by email at : [email protected]

Work Location(s)

Number of offers available

1

Company/Institute

Institut de Génétique Moléculaire de Montpellier (IGMM)

Country

France

City

Montpellier

Postal Code

34090

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Montpellier

Website

http://www.umontpellier.fr/

Street

163 rue Auguste Broussonnet

Postal Code

34000

E-Mail

[email protected]

STATUS: EXPIRED