Post-doc in cell biology and mechanobiology

28 Mar 2024
Job Information

Organisation/Company

Institute of Pharmacology and Structural Biology

Research Field

Biological sciences » Biology
Physics » Biophysics

Researcher Profile

First Stage Researcher (R1)
Recognised Researcher (R2)
Established Researcher (R3)
Leading Researcher (R4)

Country

France

Application Deadline

18 Apr 2024 - 12:00 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The candidate will join the team "Phagocyte architecture and dynamics" at the IPBS. He/she will develop a research project aiming at understanding the mechanical functioning of phagocytosis. This study will be carried out under the supervision of Renaud Poincloux.

The postdoctoral fellow will be in charge of the development of the project and will adopt a multidisciplinary strategy combining cell biology approaches, force measurements, quantitative 3D imaging and cryo-electron tomography. He/she will design, implement and interpret the experiments. For this, he/she will work independently but also with other team members and collaborators for the needs of the project. He/she will participate in the dissemination and valorization of the results and will carry out the bibliographic watch of the field.

The successful candidate must have a PhD. Experience in cell biology, biophysics and/or imaging is expected. We are looking for an autonomous, rigorous, dynamic, motivated and persevering candidate. The candidate must have published scientific articles, be organized, meticulous and have a strong sense of ethics.

The project will be developed at the IPBS, which is a Joint Research Unit of the CNRS and the Paul Sabatier University (University of Toulouse). The main objective of the IPBS is the identification, characterization and exploitation of new therapeutic targets in the fields of cancer, infection and inflammation. The postdoctoral fellow will join the team led by Renaud Poincloux and Christel Vérollet, which studies the interactions between phagocytes and their environment, in physiological and pathological contexts.

6 recent publications of the team :

Mascarau M et al. (2023) Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells. J Cell Biol
Portes M et al. (2022) Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts. Elife
Jasnin M et al. (2022) Elasticity of dense actin networks produces nanonewton protrusive forces. Nat Commun
Dupont M et al. (2020) Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. Elife
Souriant S et al. (2019) Tuberculosis exacerbates HIV-1 infection through IL-10/STAT3-dependent tunneling nanotube formation in macrophages. Cell Rep
Raynaud-Messina B et al. (2018) The bone degradation machinery of osteoclasts: a novel HIV-1 target that contributes to bone loss. Proc Natl Acad Sci USA

Applications should be written in English and submitted through this interface. They should include a CV and a cover letter summarizing the candidate's interest in the position and previous experience, as well as the contact details of 2-3 scientists who could provide a recommendation.

Contact: Dr Renaud Poincloux - [email protected]

Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Skills/Qualifications

The successful candidate must have a PhD. Experience in cell biology, biophysics and/or imaging is expected. We are looking for an autonomous, rigorous, dynamic, motivated and persevering candidate. The candidate must have published scientific articles, be organized, meticulous and have a strong sense of ethics.

Specific Requirements

Applications should be written in English and submitted through this interface. They should include a CV and a cover letter summarizing the candidate's interest in the position and previous experience, as well as the contact details of 2-3 scientists who could provide a recommendation.

Contact: Dr Renaud Poincloux - [email protected]

Languages

ENGLISH

Level

Good

Research Field

Biological sciences » BiologyPhysics » Biophysics

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

CNRS/IPBS

Country

European Commission

State/Province

France

City

Toulouse

Geofield

Where to apply

Website

https://emploi.cnrs.fr/Offres/CDD/UMR5089-RENPOI-007/Default.aspx

Contact

City

Toulouse

Website

https://www.ipbs.fr/phagocyte-architecture-and-dynamics/

Street

205 route de Narbonne

E-Mail

[email protected]

STATUS: EXPIRED