Neuroscience researcher "Engineering and structure determination of neuronal protein-receptor complexes important for neurotransmission" M/F

9 Feb 2024
Job Information

Organisation/Company

CNRS

Department

Institut Interdisciplinaire de Neurosciences

Research Field

Neurosciences
Biological sciences

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

29 Feb 2024 - 23:59 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

35

Offer Starting Date

1 Mar 2024

Is the job funded through the EU Research Framework Programme?

H2020 / ERC

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The project will focus on engineering and structure determination of neuronal protein-receptor complexes that are important for neurotransmission.

The project is already in an advanced stage, which means that the candidate will be able to build quickly on a significant body of existing results

The work will involve protein production from mammalian cells, protein purification and protein chemistry, biophysical interaction analysis (SPR, BLI), engineering of protein-protein interactions, and structure determination using X-ray crystallography and cryo-EM.

Created on January 1, 2011, the Institut interdisciplinaire de neurosciences (IINS) is a joint research unit attached to the CNRS and the University of Bordeaux. With 170 staff in 14 teams, IINS combines multidisciplinary skills to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. A component of Bordeaux Neurocampus, IINS is one of the major players in the neuroscience community in Aquitaine.
This is a full-time position. The project will be carried out under the supervision and mentorship of Dr. Jonathan Elegheert.

Requirements

Research Field

Neurosciences

Education Level

PhD or equivalent

Research Field

Biological sciences

Education Level

PhD or equivalent

Languages

FRENCH

Level

Basic

Research Field

Neurosciences

Years of Research Experience

None

Research Field

Biological sciences

Years of Research Experience

None

Additional Information
Eligibility criteria

The candidate must hold a PhD degree and have less than seven years of post-doctoral experience at the start of the contract. The candidate should have a solid background in molecular biology, biochemistry and/or structural biology. Experience with (i) mammalian expression systems (HEK293 cell lines), (ii) biophysical analysis methods (surface plasmon resonance, isothermal titration calorimetry, microscale thermophoresis, bio-layer interferometry, etc.), and (iii) X-ray crystallography or cryo-EM, is preferred. The candidate should be highly motivated, a team player, and have a can-do problem-solving attitude.

Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR5297-MELDES0-200/Default.aspx

Work Location(s)

Number of offers available

1

Company/Institute

Institut Interdisciplinaire de Neurosciences

Country

France

City

BORDEAUX

Geofield

Where to apply

Website

https://emploi.cnrs.fr/Candidat/Offre/UMR5297-MELDES0-200/Candidater.aspx

Contact

City

BORDEAUX

Website

http://www.iins.u-bordeaux.fr/?lang=en

STATUS: EXPIRED