22 Mar 2024
Job Information
- Organisation/Company
Supramolecular (bio)-Inorganic chemistry group; LCBPT (UMR 8601); Université Paris Cité- Research Field
Chemistry- Researcher Profile
Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)- Country
France- Application Deadline
20 Apr 2024 - 22:00 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
Context.
The development of molecular systems emitting in the Near-Infra-Red remains an important challenge for bio-imaging. The combination of luminescence and chirality offers new routes to increase contrast and perform deeper tissue penetration of light. Supramolecular chemistry provides a promising strategy to control the chirality of NIR-emitting coordination complexes in molecular cages. The emission properties of the latter supramolecular self-assemblies should be tuned by recognition of small molecules in particular chiral ones that will allow developing applications in probing. Our aim is to synthetize tetrahedral molecular cages holding NIR emitting coordination complexes at vertices and study (i) the effect of the chirality of the assembly and (ii) the effect of encapsulation of molecule guests on emissive features and associated circularly polarized luminescence. A special focus will be put on controlling the chirality of assemblies.
Objectives.
The objectives of this thesis will be to synthetize NIR luminescent chiral metallo-cages and to study the effects of (i) the assembly, (ii) the counter anion, (iii) the ligand structure and (iv) the guest, on the photophysical and chiroptic properties. The latter properties should raise applications in innovative bio-imaging methods harnessing CP-light.
Work plan.
The student will first conduct organic synthesis of ligands before synthetizing the molecular cages by self-assembly. The effect of different chiral biases (counter anion, chiral ligand, guest) on the chirality induction will be then investigated. Then, the student will focus on analyzing the emission and chiroptic properties of cages, upon modification of ligand, counter anion and encapsulated guest.
Funding.
The 3 years of PhD. are funded by an ANR JCJC project “SupraCPL” (ANR-23-CE07-0019-01).
Application.
To apply, send your CV, the name of two former advisors and the transcript of the marks of your Master degree (1st and 2nd years).
Funding category: Contrat doctoral
3 years financed by ANR JCJC project
PHD title: Doctorat de chimie
PHD Country: France
Requirements
Specific Requirements
Solid bases on coordination chemistry, and synthesis are required.
The Master marks transcripts are crucial point for selection during the competitive examination.
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Supramolecular (bio)-Inorganic chemistry group; LCBPT (UMR 8601); Université Paris Cité
- Country
- France
- City
- Paris
- Geofield
Where to apply
- Website
https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/121550
Contact
- Website
https://lcbpt.biomedicale.parisdescartes.fr/supramolecular-bioinorganic-chemistry/
STATUS: EXPIRED
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