Deciphering the spatial representation of connected environments

Updated: over 1 year ago
Location: Tremblay en France, LE DE FRANCE
Job Type: FullTime
Deadline: 17 Aug 2022

The candidate will have to carry out the experiments, process, analyse and interpret the results and write scientific articles
-stereotactic implantation of electrophysiological systems in rodents
-vector injection to use DREADDS and optogenetic tools
-recording of electrophysiological single units in awake and free-moving animals
-implementation of behavioral tasks in rodents
-data processing and analysis
-interpretation of the results

The main objective of the project is to unravel the nature of the spatial representation when animals navigate in complex environments made of connected rooms. Experiments will consist in performing multi-site recordings in the thalamo-retrosplenial-entorhinal-hippocampal network, in animals exploring complex environments. The candidate will use a wireless system to simultaneously record head direction cells, grid cells and place cells in freely moving rats. Neural recordings will be combined with optogenetic or pharmacogenetic (DREADDS) perturbations to investigate the interactions between the different cell populations.

This 2.5 years long position is available in the SPATIAL COGNITION team at the Laboratory of Cognitive Neuroscience (https://lnc.univ-amu.fr/en ) to work on the ANR-funded CONECPSACE (leaded by Dr Pierre-Yves Jacob). . The Laboratory of Cognitive Neuroscience is housed within Aix-Marseille University located on Saint-Charles Campus in Marseille, in the center of Marseille.



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