24 May 2024
Job Information
- Organisation/Company
CNRS- Department
Unité de Glycobiologie Structurale et Fonctionnelle- Research Field
Physics- Researcher Profile
First Stage Researcher (R1)- Country
France- Application Deadline
13 Jun 2024 - 23:59 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Hours Per Week
35- Offer Starting Date
16 Sep 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The aim of the research project is to develop innovative polymer biosynthesis routes using seawater-based reaction environments. Two approaches will be considered: the use of sucrose-rich by-products from the sugar industry, and the conversion of atmospheric carbon dioxide into sucrose using marine cyanobacteria. The project aims to meet the growing demand for high value-added bio-based polymers, while minimising energy and freshwater consumption, as well as carbon dioxide emissions. The successful candidate will implement the "push-block-pull" strategy to optimise sucrose production and/or the expression of glycosyltransferases in marine cyanobacteria. The aim of this fixed-term contract will be to use metabolic engineering approaches to design cyanobacteria to serve as platforms for the production of biosourced biopolymers in photobioreactors.
- The successful candidate will generate knock-out mutants using CRISPRCas9/Cas12 technology as well as strains expressing heterologous proteins (e.g. glycosyltransferases). -He or she will assess possible stresses or viability problems during the design stages. - He or she will be responsible for writing experimental reports and protocols, as well as passing on the knowledge acquired in the course of his or her work. -He or she will also be involved in writing the research articles resulting from this project. - He or she will also be responsible for managing the stocks of biological reagents and consumables needed to carry out the experiments. - He or she will have to comply with current health and safety regulations.
The staff will be assigned to the Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Lille, FST, under the direction of Professor Colleoni Christophe within the “microbial genetics” team. The candidate will have access to all research equipment via the various technological platforms of the University of Lille and the CNRS. The mission is part of a collaborative research project; travel to INSA Toulouse will be expected.
Requirements
- Research Field
- Physics
- Education Level
- PhD or equivalent
- Languages
- FRENCH
- Level
- Basic
- Research Field
- Physics
- Years of Research Experience
- None
Additional Information
Eligibility criteria
The skills sought include: - A solid mastery of molecular biology tools (transformation, CRISPR/cas, etc.) applied to cyanobacteria. - In-depth knowledge of the physiology of cyanobacteria. - Experience with photobioreactors will be appreciated. - Have a doctorate in one of the following fields: microbiology, cyanobacteria, biotechnology - Essential skills in scientific and technical English necessary for understanding experimental protocols.
- Website for additional job details
https://emploi.cnrs.fr/Offres/CDD/UMR8576-MARRAT-047/Default.aspx
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Unité de Glycobiologie Structurale et Fonctionnelle
- Country
- France
- City
- VILLENEUVE D ASCQ
- Geofield
Where to apply
- Website
https://emploi.cnrs.fr/Candidat/Offre/UMR8576-MARRAT-047/Candidater.aspx
Contact
- City
VILLENEUVE D ASCQ- Website
http://ugsf-umr-glycobiologie.univ-lille1.fr
STATUS: EXPIRED
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