Contract researcher in polysaccharide biology M/F

24 May 2024
Job Information

Organisation/Company

CNRS

Department

Unité de Glycobiologie Structurale et Fonctionnelle

Research Field

Physics

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

13 Jun 2024 - 23:59 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

35

Offer Starting Date

16 Sep 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The aim of the research project is to develop innovative polymer biosynthesis routes using seawater-based reaction environments. Two approaches will be considered: the use of sucrose-rich by-products from the sugar industry, and the conversion of atmospheric carbon dioxide into sucrose using marine cyanobacteria. The project aims to meet the growing demand for high value-added bio-based polymers, while minimising energy and freshwater consumption, as well as carbon dioxide emissions. The successful candidate will implement the "push-block-pull" strategy to optimise sucrose production and/or the expression of glycosyltransferases in marine cyanobacteria. The aim of this fixed-term contract will be to use metabolic engineering approaches to design cyanobacteria to serve as platforms for the production of biosourced biopolymers in photobioreactors.

- The successful candidate will generate knock-out mutants using CRISPRCas9/Cas12 technology as well as strains expressing heterologous proteins (e.g. glycosyltransferases). -He or she will assess possible stresses or viability problems during the design stages. - He or she will be responsible for writing experimental reports and protocols, as well as passing on the knowledge acquired in the course of his or her work. -He or she will also be involved in writing the research articles resulting from this project. - He or she will also be responsible for managing the stocks of biological reagents and consumables needed to carry out the experiments. - He or she will have to comply with current health and safety regulations.

The staff will be assigned to the Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Lille, FST, under the direction of Professor Colleoni Christophe within the “microbial genetics” team. The candidate will have access to all research equipment via the various technological platforms of the University of Lille and the CNRS. The mission is part of a collaborative research project; travel to INSA Toulouse will be expected.

Requirements

Research Field

Physics

Education Level

PhD or equivalent

Languages

FRENCH

Level

Basic

Research Field

Physics

Years of Research Experience

None

Additional Information
Eligibility criteria

The skills sought include: - A solid mastery of molecular biology tools (transformation, CRISPR/cas, etc.) applied to cyanobacteria. - In-depth knowledge of the physiology of cyanobacteria. - Experience with photobioreactors will be appreciated. - Have a doctorate in one of the following fields: microbiology, cyanobacteria, biotechnology - Essential skills in scientific and technical English necessary for understanding experimental protocols.

Website for additional job details

https://emploi.cnrs.fr/Offres/CDD/UMR8576-MARRAT-047/Default.aspx

Work Location(s)

Number of offers available

1

Company/Institute

Unité de Glycobiologie Structurale et Fonctionnelle

Country

France

City

VILLENEUVE D ASCQ

Geofield

Where to apply

Website

https://emploi.cnrs.fr/Candidat/Offre/UMR8576-MARRAT-047/Candidater.aspx

Contact

City

VILLENEUVE D ASCQ

Website

http://ugsf-umr-glycobiologie.univ-lille1.fr

STATUS: EXPIRED