ANALYSIS OF THE CELLULAR BEHAVIOR OF NEUROMESODERMAL PROGENITORS

Updated: 11 months ago
Job Type: FullTime
Deadline: 30 Jun 2023

28 May 2023
Job Information
Organisation/Company

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Research Field

Biological sciences
Researcher Profile

First Stage Researcher (R1)
Country

France
Application Deadline

30 Jun 2023 - 23:00 (UTC)
Type of Contract

To be defined
Job Status

Full-time
Hours Per Week

To be defined
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Neuromesodermal progenitors (NMPs) represent a population of stem cells located in the vertebrate embryonic tail. These stem cells are crucial for building both nervous and musculoskeletal systems. Interestingly, NMPs can be derived and differentiated from human pluripotent stem cells, making them a great hope for tissue engineering. However, we still do not know how these stem cells are coordinating their differentiation programs with the morphogenetic events leading to mesodermal and neural tissue organization. We recently showed that NMPs display unexpectedly high levels of cell-to-cell heterogeneity, a property that we found to be related to their capacity to auto-organize in tissues. We will use bird embryo as a model system, combining state-of-the-art primary culture, single-cell RNA seq, live imaging, and functional studies by electroporation we aim to understand the cellular behavior involved in progenitor segregation and tissue production.


Requirements
Additional Information
Work Location(s)
Number of offers available
1
Company/Institute
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Country
France

Where to apply
Website

https://jobrxiv.org/job/centre-national-de-la-recherche-scientifique-27778-anal…

Contact
Website

https://cbi-toulouse.fr/eng/equipe-benazeraf

STATUS: EXPIRED

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