2 (+1)-years Post-Doc position : Carmen Buchrieser’s lab “Biology of Intracellular Bacteria”, Department of Microbiology, Institut Pasteur, Paris

Institut Pasteur, France

Updated: about 2 years ago
Deadline: ;

A postdoctoral position is available at the Institut Pasteur in Paris to analyse the structure and content of extracellular vesicles shed by Legionella pneumophila (Lp-EVs) in vitro and in cellulo.

Our lab at the Institut Pasteur has recently shown that Legionella pneumophila sheds membrane vesicles that transport cargo such as proteins and RNAs in the host cell that helps to achieve better intracellular replication of L. pneumophila. In the here proposed project we have joined forces with the group of G. Lavieu to:

1) characterize this transport at the cellular and molecular levels

2) and to identify the core machinery responsible for L. pneumophila– derived EV delivery.

As part of this project, we search for a postdoc who will employ Cryo EM of and cryo-CLEM of Lp-EVs and hEVs to analyse their structure and cargo.


Where? 

The project will be carried out in the Biology of Intracellular Bacteria lab expert in biology of Legionella and the analyses of extracellular vesicles and the Nanoimaging Core facility at the Institut Pasteur and in close collaboration with the group of G. Lavieu  at the Université de Paris , expert of human extracellular vesicles (exosomes) (hEvs).


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