Postdoctoral Researchers at the Medical Systems Biology group

Updated: 7 months ago
Deadline: 21 Aug 2023

Laboratory of Prof. Jussi Taipale at the Medical Systems Biology group at the Applied Tumour Genetic Program at University of Helsinki, Faculty of Medicine invites applications for the position of
POSTDOCTORAL RESEARCHERS (two positions)

Our research group is part of the Academy of Finland's Centre of Excellence in Tumour Genetics Research. The laboratory focuses on the study of transcriptional control of cell growth, using functional genomics and systems biology. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, using this information to identify regulatory elements that control cell growth during normal development or in cancer.

Qualifications

Applicants with a doctoral degree and strong background in molecular biology/bioinformatics who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.

What we offer

The appointment will be initially for two years starting from September 2023. Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .

How to apply

Please submit your application as a single PDF file containing your CV, publication list including impact factors and two letters of reference through the University’s electronic recruitment system by clicking “Apply for the position” link below. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi . The deadline for applications is 21 August 2023.

For further information on the position, please contact Petros Papadopoulos (petros.papadopoulos (at)helsinki.fi).

For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at)helsinki.fi).


Selected publications from Taipale lab:
Sahu et al. Sequence determinants of human gene regulatory elements. Nature Genetics, 2022, April 283–294.

Sahu et al. Human cell transformation by combined lineage conversion and oncogene expression. Oncogene. 2021, Sept, 5533-5547.

Zhu et al. The interaction landscape between transcription factors and the nucleosome. Nature. 2018, Oct, 76-81.

Yin et al. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 2017, May 5;356(6337).

Yan et al. Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell, 2013, 154, 801-13.

The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master's Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.

The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.

Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.



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