Postdoctoral Fellowship in bioinformatics and genetic epidemiology

Updated: over 1 year ago
Deadline: 26 Aug 2022

A two-year postdoctoral fellowship is available at the Section for Computational and RNA Biology, Department of Biology, University of Copenhagen.

The position will be available from November 1, 2022.

The specific projects involve analyzing large amounts of multi-omic data from several ethnic groups, including Danes, Pakistani and Greenlanders. The multi-omic data include whole genome sequencing, RNA sequencing data, gut microbiome, proteomics and metabolomics data. The focus is either on comparing different ethnic groups or on the Greenlandic population where we have both multi-omic data, deep phenotype data and whole genome data for a large cohort.

The projects are part of a series of large-scale genetic studies in the Greenlandic population and other ethnic groups with the aim of unravelling the role of genetics, diet, physical activity, and the gut microbiome in metabolic health and disease, both separately and in interaction. The applicant is expected to collaborate on several other projects as well.

Key publication relevant for the Greenlandic study
Moltke et al. Nature, 2014 512(7513);190-3
Moltke et al. Am. J. Hum. Genet.: 2015, 96(1);54-69

Fumagalli et al. Science, 2016 , 349(6254);1343-7
Grarup et al. Nature Genetics 2018, 50(2);172-174
Waples et al. Current Biology 2021,31(10):2214-2219
Andersen et al.
Gastroenterology 2022; 162(4):1171-8
Jørsboe et al. Human Genetics and Genomics Advances 2022. In press.

Research environments
The position is jointly in the groups of professor Anders Albrechtsen and associate professor Ida Moltke at the Section for computational and RNA biology. The groups have a long-term collaboration working with disease mapping and population genetics, most notably within the Greenlandic population. Both groups of Ida Moltke and Anders Albrechtsen are developing and applying statistical and computational approaches for analysis of large scale genomic data, including methods for association studies, for detecting and correcting for population stratification, for detecting selection on disease susceptibility genes, for modeling identity by descent and various topics for analysis of large scale sequencing data.

For more information, please see www.popgen.dk  

In addition, the projects that the successful candidate will be working on are a part of a collaboration with the clinical group of Dr. Professor Torben Hansen, who works with genetic, microbiome and metabolome studies in monogenic diabetes, childhood obesity and large-scale genetic epidemiology studies. For more information, see tinyurl.com/ycx833rt

Qualifications
The postdoc will be expected to participate both in the bioinformatics analysis of sequencing data as well as in the interpretation, writing and leading the projects. Some flexibility in the tasks is possible depending on the skills and interests of the candidate.

To be considered, applicants must:

  • Have a PhD in bioinformatics, quantitative genetics, population genetics, statistical genetics or a similar field 
  • Have experience in working with high throughput sequencing data 
  • Be experienced with handling of large amount of genetic data

Skills of additional interest include (but not required):

  • Experience with multi-omic data
  • Experience in statistics 
  • Experience in population genetics
  • Experience with GWAS
  • Experience with running analyses using HPC
  • Experience using BASH, R, python, C/C++
  • Experience with analyses of high-dimensional data             

The working language is English, thus good English speaking, reading and writing skills are required.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

For further information please contact Anders Albrechtsen ([email protected]) or Ida Moltke ([email protected] )

Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State.

Negotiation for salary supplement is possible.

The application, in English, must be submitted electronically by clicking APPLY NOW below.

Please include

-                     Curriculum vitae
-                     Diplomas (Master and PhD degree or equivalent)
-                     Research plan – description of current and future research plans
-                     Complete publication list
-                     Separate reprints of 3 particularly relevant papers

The deadline for applications is 26 August 2022, 23:59 GMT +2.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/


Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.



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