Postdoctoral fellow in multi-omics investigation of cardiac disease in humans

Job Description

The Cardiac Proteomics Group at Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen wishes to appoint a talented postdoctoral fellow for a 2-year position for a joint proteomics, transcriptomics, and genomics project investigating the underpinnings of cardiac disease. The postdoctoral fellow will use quantitative proteomics-based approaches to identify the molecular changes in cardiac disease in an unbiased manner from human heart biopsies. From the same biopsies, the fellow will obtain WGS and single cell transcriptomics data and integrate this information across the omics datasets acquired. This will lead to investigation of the cardiac disease at unprecedented molecular level.

We are seeking a highly motivated postdoctoral fellow to join our team, who will work on a large scale project investigating the molecular changes in heart disease by state-of-the-art measurements from human heart biopsies.

Qualification Requirements

• Holds a Ph.D. in a highly quantitative field including but not limited to Bioinformatics, Computer Science, Applied Mathematics, Biomedical Engineering or Computational Physics
• Ambitious, creative, independent and self-driven
• Hands on skills and expert knowledge in one or more of the following areas:
  • Experience with downstream analysis of data dependent/independent acquisition (DDA/DIA) LC-MS/MS data
  • Experimental know-how of mass spectrometry-based proteomics (LC-MS/MS)
  • Analytical know-how of single cell/bulk RNAseq data
  • Analytical experience with genomics data
  • Experience integrating different types of omics data
  • Excellent programming skills, fluency in Python and R programming languages as well as sound knowledge of statistical data analysis

• Experience analyzing data from fixed, embedded tissue samples is a strength
• Prior experience within molecular cardiac research is an advantage but not a requirement
• Good communication skills in English, both oral and written

The preferred applicant should have an excellent academic track record, solid research experience and be highly motivated to deploy diverse strategies to extract novel findings of importance to cardiac pathophysiology. Previous research experience in a competitive environment is required.

Our group and environment
The candidate will be part of the Cardiac Proteomics group led by Professor Lundby at the Department of Biomedical Sciences at the University of Copenhagen, Denmark. The successful candidate will be working in a team of scientists across multiple scientific fields focused on improving our molecular understanding of cardiac pathophysiologies. Our facilities include state-of-the-art laboratories and core facilities as well as modern office spaces. The position provides a unique opportunity to develop expertise in cutting edge quantitative mass spectrometry-based proteomics, data analysis of large datasets and integration of multi-omics datasets. Striving for academic excellence, collegial respect and freedom tempered by responsibility, we offer creative, friendly and stimulating working conditions in a dynamic and strong scientific environment where you get the opportunity to plan your work independently to further your professional and personal development.

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations (AC). Any negotiation for allowance will be agreed with the relevant union.

Workplace and period of employment
Workplace is located at Maersk Tower, The Panum Institute, University of Copenhagen, Denmark. The period of employment is 2 years. Suggested start date is primo 2022.

Further information
Further information may be obtained from Professor Lundby: [email protected] .

You can read more about Cardiac Proteomics Group at www.lundbylab.com

You can read more about the Department of Biomedical Sciences at www.bmi.ku.dk

Application procedure
Interested candidates are encouraged to submit an online application by clicking “APPLY NOW” below no later than December 2rd 2021.

The File Must Include

Applications must be submitted as one PDF file containing all materials to be given consideration. Attach all your materials in English in one PDF file. The application should contain:

• Application (cover letter)
• CV
• Relevant diplomas (an official translation into English)
• List of publications
• Contact details for two referees

Applications and enclosures received after the deadline will not be considered.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at www.employment.ku.dk

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.