Postdoc in proteomics at Novo Nordisk Foundation Center for Protein Research

A highly attractive postdoctoral position is available in the Choudhary group at the Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk ), University of Copenhagen. Expected start date on 1 January 2023 or after agreement.

About the groups
The Choudhary lab is technically and internationally diverse and embedded in an excellent environment that supports high-quality research and encourages interdisciplinary collaboration. The Choudhary lab conducts experimental and computational research using interdisciplinary, state-of-the-art technologies, including quantitative proteomics, next-generation nucleic acid sequencing, advanced microscopy, CRISPR-based genome editing, and bioinformatics. The lab uses diverse cell models, including embryonic stem cells and their differentiated derivatives.

The Choudhary lab shares the laboratory space with the group of Prof. Matthias Mann and works closely with his group. The group extensively collaborates with top-level international researchers, routinely publishes in top-ranked journals, and has an outstanding track record in training the next generation of researchers.

We are now looking for enthusiastic candidates with a PhD and/or MD (i.e. level of education corresponding to the Danish PhD degree).

Project description
Our group is interested in using mass spectrometry-based quantitative proteomics for global analysis of lysine acetylation and ubiquitylation. Previously, we used this technique to map lysine acetylation and ubiquitylation sites and to quantify their relative changes after diverse perturbations. The current project builds on our previous work and aims to further understand the scope and regulation of lysine acetylation and ubiquitylation. The candidate will perform laboratory experiments and use quantitative mass spectrometry for global mapping of lysine acetylation and/or ubiquitylation, as well as changes in the proteome expression. The candidate will also perform bioinformatic analyses of the mass spectrometry data.

Qualifications
The candidate should have demonstrated excellent scientific productivity, evidenced by high-quality research publications, be able to conduct independent and creative research, and show good interpersonal and communication skills.

• The candidate is required to have a PhD/MD level of education corresponding to the Danish PhD degree in natural or medical science. Candidates who have not yet submitted their PhD thesis can apply, but submit their PhD thesis before the indicated start date (1 January 2023).
• Excellent scientific track record, including at least one publication in a high-quality, peer-reviewed international journal. Pre-prints can be counted for fulfilling this requirement.
• Expert knowledge in one or more of the following areas is required: 
  • Experience in culturing mammalian cells
  • Hands-on experience in mass spectrometry sample preparation
  • Experience in mass spectrometry-based global analysis of PTMs, such as acetylation or ubiquitylation
  • Strong background in the statistical analysis of large-scale proteomics data
• Good communication skills, both oral and written.
• An analytical aptitude for devising innovative scientific or technical solutions.
• Demonstrate enthusiasm, motivation, flexibility and confidence.

For further information, please contact Professor Chuna Ram Choudhary, email: [email protected] .

Place of employment and work
The employment is at CPR (www.cpr.ku.dk ), University of Copenhagen, located in central Copenhagen. In the past 10 years, CPR has established itself as a top-level research institute in protein signaling and network biology research. The research environment at CPR is ambitious and international, with approx. 30 different nationalities are currently represented. The Center comprises modern laboratories, supercomputer resources, and state-of-the-art research facilities. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center. Denmark is often ranked as the happiest nation and Copenhagen is consistently ranked as one of the best cities for living. For more information on working and living in Denmark visit www.ism.ku.dk   (International staff mobility) and www.workingconditions.ku.dk .

Terms of salary and employment
Salary, pension, and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts around 35.600 DKK approx. 4,780 €, plus 17.1 % in pension contribution. Depending on qualifications, a supplement may be negotiated.

The Danish Ministry of Finance and the Danish Confederation of Professional Associations (AC) have agreed on a protocol that makes it possible for all international researchers employed by the University to achieve a pension exemption, where the pension can be paid out as salary. For more information about the different pension schemes www.ism.ku.dk/onarrival/pension/

Expected start date: 1 January 2023.
Duration: The duration of the full-time position is 2 years.

Application procedure
Your online application must be submitted in English by clicking ‘APPLY NOW’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Cover letter

2. Curriculum vitae, incl. educational qualifications, experience, and a list of publications

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do. If the degree is not yet awarded, it is sufficient to mention in the cover letter when the applicant expects to submit the thesis, and/or receive the qualifying degree

4. Names and contact details for 2 referees

Application deadline:  14 October 2022, 23.59 pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements.

After the expiry of the application deadline, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at www.employment.ku.dk .

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

For further information about the position or the process or if you experience any technical difficulty with the online submission system, please contact SUND HR: [email protected]

CPR and the University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.