Fermentation Specialist - DTU Biosustain

Updated: 6 months ago
Deadline: The position may have been removed or expired!

The department Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) at the Technical University of Denmark is seeking a highly skilled and enthusiastic Fermentation Specialist.

The proposed start date of the position is in 2023 as soon as possible. This position will be placed at DTU Biosustain, in the Integrated Fermentation Platform (iFP) of the Biofoundry, working with the aim to bridge the gap between academic metabolic engineering projects from cell factories and commercial application. We aim at establishment and integration of a DBTL (Design-Build-Test-Learn) workflow, from synthetic biology through genetic engineering, bench-scale fermentations, and scale-up process design/development towards gate milestone driven project until successful release into the market. The Biofoundry has a total staff of 30 employees, comprising of a highly motivated team of Engineers, Scientists and Technicians to tackle this challenging task.

Responsibilities and tasks 
As a Fermentation Specialist, you will be part of the iFP group and primarily focus on performing microbial fermentations at different scales (0.2 mL – 10 L) applying different strategies (batch, fed batch, chemostat) and physiological characterization of the corresponding microorganisms. You will also carry out experiments independently and contribute to elucidate the robustness of microbial cell factories for industrial applications. You will actively take part in translational projects, aiming towards microbial production/ platform strains that are generated within the Biofoundry. 

Qualifications
Candidates should have a Master degree (in Biochemical Engineering/Industrial Biotechnology) or equivalent.

We are looking for a candidate with the following solid background/experience in

  • Designing, running, controlling batch, fed batch and chemostat cultivations ideally for both bacteria and yeast, from micro-Liter to Liter scale. 
  • Experience in running high throughput bioreactor platforms (for e.g., ambr®250) and operating bioprocess software such as Lucullus®.
  • Experience in physiology and cellular metabolism of yeast and bacteria.
  • Experience in the application of Design of Experiments, application of bioprocess design principles in bioprocess development.
  • Experience in automating workflows with different types of liquid handlers (for e.g., Tecan)
  • Scale-up and scale-down strategies of high-cell-density microbial fermentations.
  • Rapid sampling and quenching methods to measure intracellular/extracellular metabolites in both bacteria and yeast.
  • Interpretation of fermentation data including transcriptome/ metabolome data obtained during and after fermentation processes with appropriate metabolic/bioreactor models.
  • Experience with software programs for data analysis and modelling (R, MATLAB or Python).
  • Ability to work simultaneously on different projects with good planning/organisation skills. 
  • Excellent collaboration & communication skills (English).

We look forward to a candidate who

  • Enjoys working with complex topics.
  • Thrives on collaboration/teamwork and focused on the process as well as the outcome.
  • Believes in dialogue and feedback as the best foundation for sound decision-making.
  • Strives to develop talent amongst others. 

What we offer in return
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation, and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility. 

Salary and terms of employment
The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. 

You can read more about career paths at DTU here .

Further information 
Further information may be obtained from Suresh Sudarsan, [email protected]

You can read more about the department at www.biosustain.dtu.dk .

Application procedure
Please submit your online application no later than 15 September 2023 (23:59 Danish time)

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Diploma (Bachelor/Master/Advanced courses)

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion, or ethnic background are encouraged to apply.

The Department of DTU Biosustain is located at DTU Lyngby campus. The center has approx. over 300 employees and has established a world-class environment for research into the design and development of cell factories. The goal is to further increase its socio-economic impact by developing microbial strains to significantly improve bio-sustainability. Biotechnology will be a key element in the green transition, and thus, the Center is a good example to promote sustainable products and processes in Denmark.

The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics, and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods. 

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.



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