Assistant Professor to relate Protein Biophysics to Genomics and Human Metabolic Health and Disease Phenotypes

Updated: about 1 month ago
Deadline: 01 Nov 2020

Novo Nordisk Foundation Center for Basic Metabolic Research

Faculty of Health and Medical Sciences

University of Copenhagen

We are seeking a highly motivated and dynamic researcher with expertise in leading analysis and interpretation of high throughput genomic data (genome wide association arrays, exome chip, and exome/genome sequencing) to work in the newly established PRISM Centre: Protein Interactions and Stability in Medicine and Genomics. The position is a 4-year position to start 1 February 2021.

Background

The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is a vibrant international research environment with a focus on interdisciplinary collaboration. Our researchers share a common purpose as they seek to transform the basic understanding of the mechanisms involved in metabolic health and disease to accelerate this knowledge toward new prevention and treatment strategies. The Center’s research has resulted in seminal discoveries as to how genes, hormones, and environmental factors influence metabolic health and disease throughout life. You can read more about us here www.cbmr.ku.dk .

Our group and research

The Hansen Group investigates the human genome and the human global microbiome to characterize the impact of these genomes on health and disease and to identify interactions between the host and the microbiome. You can read more about the Hansen Group here .

Project description

About the PRISM centre and research environment:

The PRISM Centre is funded via a six-year Novo Nordisk Foundation Challenge grant. The research within PRISM bridges protein biophysics and genomics using computational and experimental methods with the ultimate goal of translating this knowledge into a clinical setting. In PRISM, we will combine developments in structural biology, protein folding, high-throughput experiments, computational biophysics and genomics. We hope to transform our current view of how genomic variation perturbs the stability, folding and function of proteins. In turn, we can use such information to understand, diagnose and ultimately treat human diseases. PRISM is a collaboration between three research groups at the Department of Biology, Copenhagen (led by Kresten Lindorff-Larsen, Amelie Stein, Rasmus Hartmann-Petersen), and Michele Vendruscolo (University of Cambridge, UK), Douglas M. Fowler (University of Washington, US) and Torben Hansen (Novo Nordisk Foundation centre for Basic Metabolic Research (CBMR), DK).

Your job

Your responsibilities will include analysis of high throughput genomic data including whole exome and genome sequencing from cohorts with childhood obesity, population isolates and consanguineous families as well as UK Biobank and other public resources. It will also include a translation of the genetic results combined with computational and experimental results into physiological outcomes especially in relation to the development of diabetes and obesity. You will have a solid physiological background as well as profound genetic understanding. In addition, you must have excellent communication and organisational skills as you will contribute to collaborative work with colleagues in PRISM and CBMR. As part of working at the University, the position will also entail teaching obligations.

Profile

We are looking for a highly motivated and enthusiastic scientist with the following competencies and qualifications:

  • PhD in genetics or a closely related discipline
  • High level of proficiency in programming and experience in applying statistical methods to genomic data
  • Experience with the analysis of high throughput genomic data (genome wide association arrays, exome chip, exome/genome sequencing)
  • The ability to interpret genetic results in a physiological and clinical setting
  • Previous teaching experience will be considered an advantage
  • An ambitious, independent and critical mind-set
  • Experience in experimental design and planning of experiments
  • Demonstrated capacity for effective team work  
  • Postdoctoral experience with proven track record showing scientific productivity in peer reviewed journals
  • Experience in supervising research staff at different levels.
  • Excellent English communication skills, both written and oral

Required qualifications

Six overall criteria apply for assistant professor appointments at the University of Copenhagen. The six criteria (research, teaching, societal impact, organisational contribution, external funding and leadership) are considered a framework for the overall assessment of candidates. Find information about each criteria here https://employment.ku.dk/faculty/criteria-for-recognising-merit .

Place of employment

The place of employment is at Novo Nordisk Foundation Center for Basic Metabolic Research, Maersk Tower, Faculty of Health and Medical Sciences at University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment.

Terms of employment

The employment as Assistant Professor is a full time and fixed-term position for 4 years. Starting date is 1 February 2021.

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of 19 December 2020.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information please contact Research Coordinator Lise Ryborg at lise.ryborg@sund.ku.dk . For questions regarding the recruitment procedure, please contact SUND HR CBMR at SUND-HR-CBMR@sund.ku.dk .

International applicants may find these links useful www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/ . 

Application procedure

Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (max. one page)
  • CV incl. education, work/research experience, language skills and other skills relevant for the position
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do
  • List of publications
  • Teaching portfolio if applicable(Guidelines: https://employment.ku.dk/faculty/recruitment-process/job-application-portfolio/ )

Please note: It is mandatory to upload a teaching plan in the online application form. Should you not have a teaching plan, please upload a blank document in this box instead.

Application deadline: 1 November 2020 at 23.59pm CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether an unbiased assessor has passed their application for assessment. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/ .

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.


Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.


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