A Postdoctoral position in Cellular Stress Signaling at Center for Healthy Aging, the Department of Cellular and Molecular Medicine (ICMM)

A postdoctoral position is available in Cellular Stress Signalingat Center for Healthy Aging at the Department of Cellular and Molecular Medicine (ICMM ).
The position is for 2 years and is available from 1 December 2022 or upon agreement.

Job description
The healthy life of the human organism depends on the long-term fitness of its smallest basal constituents, our cells. When deregulated, the pathologic accumulation of genetic mutations and malfunctioning macromolecules alters or compromises cellular function to promote cancer or premature ageing. Conversely, normal ageing of the human organism is associated with the time-dependent decrease in cellular fitness, caused by gradual loss of genomic integrity, and accumulation of misfolded and dysfunctional macromolecules. To protect cells from harmful environmental effects, all organisms have developed elaborate surveillance and response mechanisms to counteract such threats.

The aim of the research group is to understand the molecular details of these pathways, with an emphasis on MAP kinase induced cellular stress responses. Such work is expected to uncover novel insights into the all-important mechanisms of cellular maintenance and adaptation, which may ultimately be exploited therapeutically to prevent or remedy aging-related diseases.

We have recently uncovered an unexpected role for ribosomal stress signaling pathways in metabolic regulation in diverse mouse tissues. Using our different mouse knockout lines, the candidate is expected to contribute to the further characterization of these metabolic defects. The precise contents of the postdoc project will be defined through discussions with the selected candidate.

Scientific environment
The Department of Cellular and Molecular Medicine (ICMM) offers an ambitious scientific environment, with many different nationalities represented. ICMM aims to produce research with high international impact focusing on the functional cell, its genetic components, and molecular cellular mechanisms in a medical context.
ICMM currently comprises five research programmes, three high profile Research Centers as well as a number of international research groups. The scientists at ICMM are involved in high quality research based undergraduate and graduate teaching programs at the University of Copenhagen.

The University of Copenhagen encourages career development of its postdoctoral fellows, and the position carries an obligation to conduct some undergraduate teaching and associated examinations within the Medical School.

You can read more at https://icmm.ku.dk/english/ .

Qualifications
Highly motivated and ambitious candidates are encouraged to apply.

Required qualifications:

• A PhD degree in biomedicine or equivalent relevant discipline.
• Experience with animal work.
• Knowledge of techniques such as establishment of intestinal organoids, isolation of primary hepatocytes and metabolic characterization of mice will be considered a distinct advantage but is not a requirement.
• Proven ability to present and publish research data.

Terms of employment
The average weekly working hours are 37 hours per week. The position is a fixed-term position limited to a period of 2 years.

Salary, pension, and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or another relevant organisation. Currently, the monthly salary for a postdoctoral researcher starts at DKK 35,728 / approx. EUR 4,763 (October 2022/-level). Depending on qualifications a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions
For further information about the position, please contact Simon Bekker-Jensen by e-mail: [email protected] .

Foreign applicants may find these links useful: www.ism.ku.dk (International Staff Mobility) and www.workindenmark.dk .

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

Deadline for applications: Thursday 13 October 2022, 23.59 p.m. CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/ .

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The Faculty of Health and Medical Sciences comprises approximately 8,000 students, 1,790 PhD students and 5,100 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.