A Postdoc position (molecular biologist) is available in the Grønbæk Group at The BRIC Institute

Updated: about 2 months ago
Deadline: 13 Oct 2022

We are searching for a skilled postdoc/molecular biologist with specific interest in investigating the underlying mechanisms of normal and malignance hematopoiesis with a focus on the genetics of hereditary MDS/AML.

Our research/The group
The focus of the Grønbæk group is Translational Hematology. The group is affiliated with both Biotech Research and Innovation centre (BRIC), Rigshospitalet (Central Copenhagen University Hospital), and University of Copenhagen.

Our overall aim is to understand the molecular mechanisms of hematological cancers, and based on this; to design, develop and implement novel, scientifically based, clinical trials, with a strong focus on epigenetic therapies. This is done by bridging between clinical research at Rigshospitalet and the basic cancer biology research at BRIC, and in international collaborations with, among others, the van Andel Research Institute, Michigan, USA and the Nordic MDS study group.

Our location at the Copenhagen Biocentre/BRIC provides optimal conditions for interaction with the basic scientists at BRIC. The group currently consists of 11 scientists, MD/scientists, and students, one clinical research coordinator, 2 research nurses and two laboratory technicians.

Your job
The project focus on functional genetics of hereditary myeloid cancers.  We are searching for a skilled molecular biologist who is very interactive and enjoys collaborations with other scientists – including younger scientists and clinician scientists

Your tasks will include:

  • Laboratory work: Develop and analyze transgenic mouse models, Flow cytometry, cell line and primary cell culture.
  • Develop cellular remodels of diseases using genome editing techniques, including the newly developed CRISPR-SurF technology
  • Perform molecular techniques including DNA/RNA isolation, PCR, ddPCR, RNA-seq, ATAC-seq and DNA methylation.
  • Develop and perform protein analyses technique including Western blotting, Mass-spectrometry and ChIP-seq.
  • Analyze large sequencing data using R language.
  • Participate in grant and manuscript writing.
  • Present at local and international meetings.
  • Supervising lab techniques to new lab members and students
  • Collaboration with both scientists and clinicians.

Start: 1 January 2023

Duration: 2 years

We expect you to be a highly motivated and highly ambitious, independent scientist with the following qualifications:

  • A PhD in Life Sciences with a preferred focus on investigating molecular mechanism of disease.
  • A strong background in mechanisms of normal and malignance hematopoiesis and molecular hematology techniques
  • Comprehensive lab skills in molecular and cellular biology techniques.
  • Experience with cellular remodelling and genetic editing techniques including CRISPR-Cas9 technology.
  • Documented experience in in vivo mouse models experimentation and analyses.
  • Strong publication and presentation record in peer reviewed journals and international conferences.
  • Excellent written and spoken English skills
  • Very collaborative
  • Good social skills.

For further information regarding the position, please contact Professor Kirsten Grønbæk, kirsten.groenbaek@regionh.dk ;  phone + 4535456086 / +4525211598

Place of employment
The workplace is at the Bartholin Institute which is part of Rigshospitalet, University of Copenhagen. The Bartholin Institute is located at Copenhagen Biocentre/BRIC, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities (animal unit, flow cytometry, in vivo imaging, NGS, etc.) shared between the 23 research groups at BRIC (www.bric.ku.dk ) and the neighbouring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD.

Terms of salary and employment
The average weekly working hours are 37 hours per week. Starting date is 1 January 2023, and the position is for 2 years. 

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,000 DKK/approx. 4,700 EUR (October 2021 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (max. one page).
  • CV incl. education, work/research experience, language skills and other skills relevant for the position.
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  • List of publications.
  • Deadline for applications: 13 October 2022, 23.59pm CET
    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further process
    After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

    Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

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