Protein Researcher / Senior Protein Researcher

The Loschmidt Laboratories of protein engineering (https://loschmidt.chemi.muni.cz/peg/ ) are a vibrant environment where key issues related to protein science and molecular design are tackled. Within the frame of a collaborative multidisciplinary research network, we are currently looking for a highly skilled and motivated protein scientist to join our structural biology team to investigate the molecular mechanisms of key protein players involved in human diseases (e.g. Alzheimer’s disease), and to design new therapeutic ways.

Main duties and responsibility description

Working as part of a multidisciplinary team, you will be responsible for molecular cloning & gene assembly, protein production, characterisation and structure determination to support our projects across our protein engineering areas. The role is lab-based and requires the ability to independently develop rational experiments and trouble shoot when required. Dependent on experience, other responsibilities will include lab & project management, report & manuscript writing.

For more information, please contact Martin Marek at [email protected]

Selected publications

• Nature Communications 12: 3616 (2021)             Chem 7: 1-14 (2021)
• Chemical Science 11: 11162-11178 (2020)             ACS Catalysis 9: 4810-4823 (2019)
• ACS Catalysis 10: 1210-1223 (2020)                      J. Am. Chem. Soc. 140: 17999 (2018)

Candidate profile

• M.Sc./Ph.D. or equivalent experience with a central element of protein production for structure-based or protein-focussed programmes
• In-depth knowledge on molecular biology methods, cloning and gene assembly
• Previous experience with recombinant protein expression, purification and characterisation
• Previous experience with structural biology (crystallography or cryo-EM) appreciated
• Critical mindset, fast learner and team player
• Ability to lead a multidisciplinary project with partners in academia and industry
• Good mastery of English language

Offer

• A stimulating, diverse, international and exceptionally strong research environment
• Opportunity to work with an excellent protein engineering team
• Opportunity to learn structural biology techniques (X-ray crystallography, SAXS and cryo-EM)
• Access to synchrotron facilities (Swiss Light Source, European Synchrotron Radiation Facility)
• Opportunity to learn state of the art cryo-EM instrumentation (Talos Artica, Titan Krios)
• Support with relocation – more information here: https://www.muni.cz/en/about-us/careers/international-staff-office-iso

How to apply?

Applicants should provide the following information in English

• Detailed CV
• Motivation letter describing research interests and previous research experience
• List of publications and research achievements
• Two letters of recommendation

The deadline for applications is on February 28, 2022. A review of applications will run as they are received and until the position is filled. The shortlisted applicants complying with the requirements will be interviewed.

The application shall be submitted online via an e-application (Please, use the link in the e-Application section here: https://www.muni.cz/en/about-us/careers/vacancies/67761 ). After submitting your application successfully, you will receive an automatic confirmation email from jobs.muni.cz.

Contact: [email protected] , Šárka Nevolová.

We are looking forward to hearing from you!

More about

Masaryk University  is the second-largest university in the Czech Republic with nine faculties, more than 5000 staff, and more than 30 000 students. As a comprehensive research-intensive university with a strong international standing, our mission is to pursue top-quality research and education.

Faculty of Science MU , a proud holder of the HR Excellence in Research Award  by the European Commission, is a research-oriented faculty, offering university education (Bachelor’s, Master’s, and Doctoral degree programs) linked to both primary and applied research and high school teaching of the following sciences: Mathematics, Physics, Chemistry, Biology, and Earth sciences. We are the most productive scientific unit of Masaryk University, generating around 40 % of MU research results.

Brno , the South Moravian Region capital, situated approximately halfway between Prague and Vienna, is the largest university town in the Czech Republic and a modern metropolis with a long history and culture. Recognizing the university’s significant role in making Brno one of the most innovative cities in the CEE region, it continuously supports the South Moravian Region, the local scientific, start-up, and high-tech communities.