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The Synthetic Biology group (Prof. Codruta Ignea) in the Bioengineering department at the McGill University invites highly motivated candidates to apply for a Postdoctoral Researcher position to study terpenoid biosynthesis.
Ignea group (https://mcgill.ca/bioengineering/codruta-ignea) focuses on the biosynthesis of bioactive compounds and their production in engineered yeast targeting the largest class of natural products, the terpenoids. These compounds have found various applications as pharmaceuticals, food supplements, flavors and fragrances, biopesticides or even biofuels.
By reconstructing and optimizing target pathways and enzymes involved in terpenoid biosynthesis, we aim to achieve high yields of known compounds and produce new-to-nature molecules with potential interesting activities.
Project description:
An interdisciplinary project for the production of bioactive terpenoids in yeast cells. The project is part of an integrative program aiming to AI-driven discovery of small molecules for drug development and combines computational studies with synthetic biology, metabolic engineering and bioactivity evaluation.
The project involves gene discovery and pathway elucidation, synthetic biology, metabolic engineering and genome editing approaches for the reconstruction and optimization of target biosynthetic pathways in yeast cells, gene mining and screening of library candidates, enzyme engineering, production and characterization of target compounds.
Qualifications:
-Applicants must hold a Ph.D. with background in bioinformatics/computational biology, system, structural or synthetic biology.
- Strong expertise in genomics/transcriptomics, protein engineering, modelling, genetic/protein networks.
- Knowledge about yeast/plant genomics, specialized metabolism, or natural products is desirable but not essential.
Expected start date is June 1 2023
This is a one year contract renewable.
Salary will be commensurate with qualifications and experience.
Annual Salary:
(AMURE Post-Doctoral Fellow Researcher) $34,611.00
Hours per Week:
35 (Full time)
Location:
UQAM – Pavillon des Sciences Biologiques
Supervisor:
Assistant Professor
Position Start Date:
2023-06-01
Position End Date:
2025-05-31
Deadline to Apply:
2023-05-01
McGill University hires on the basis of merit and is strongly committed to equity and diversity within its community. We welcome applications from racialized persons/visible minorities, women, Indigenous persons, persons with disabilities, ethnic minorities, and persons of minority sexual orientations and gender identities, as well as from all qualified candidates with the skills and knowledge to productively engage with diverse communities. McGill implements an employment equity program and encourages members of designated groups to self-identify. Persons with disabilities who anticipate needing accommodations for any part of the application process may contact, in confidence, accessibilityrequest.hr@mcgill.ca .